Department of Pediatrics, Children's National Hospital, Washington, District of Columbia.
George Washington University School of Medicine and Health Sciences, Washington, District of Columbia.
Pediatrics. 2022 Aug 1;150(2). doi: 10.1542/peds.2021-055570.
Compared with population-based rates, at-risk rates (ARRs) account for underlying variations of asthma prevalence. When applied with geospatial analysis, ARRs may facilitate more accurate evaluations of the contribution of place-based social determinants of health (SDOH) to pediatric asthma morbidity. Our objectives were to calculate ARRs for pediatric asthma-related emergency department (ED) encounters and hospitalizations by census-tract in Washington, the District of Columbia (DC) and evaluate their associations with SDOH.
This population-based, cross-sectional study identified children with asthma, 2 to 17 years old, living in DC, and included in the DC Pediatric Asthma Registry from January 2018 to December 2019. ED encounter and hospitalization ARRs (outcomes) were calculated for each DC census-tract. Five census-tract variables (exposures) were selected by using the Healthy People 2030 SDOH framework: educational attainment, vacant housing, violent crime, limited English proficiency, and families living in poverty.
During the study period, 4321 children had 7515 ED encounters; 1182 children had 1588 hospitalizations. ARRs varied 10-fold across census-tracts for both ED encounters (64-728 per 1000 children with asthma) and hospitalizations (20-240 per 1000 children with asthma). In adjusted analyses, decreased educational attainment was significantly associated with ARRs for ED encounters (estimate 12.1, 95% confidence interval [CI] 8.4 to 15.8, P <.001) and hospitalizations (estimate 1.2, 95% CI 0.2 to 2.2, P = .016). Violent crime was significantly associated with ARRs for ED encounters (estimate 35.3, 95% CI 10.2 to 60.4, P = .006).
Place-based interventions addressing SDOH may be an opportunity to reduce asthma morbidity among children with asthma.
与基于人群的比率相比,风险比率(ARR)考虑了哮喘患病率的潜在差异。当与地理空间分析结合使用时,ARR 可以更准确地评估基于地点的健康社会决定因素(SDOH)对儿科哮喘发病率的贡献。我们的目的是计算华盛顿特区(DC)的 ARR 以评估其与 SDOH 的关联。
本基于人群的横断面研究纳入了 2018 年 1 月至 2019 年 12 月期间在 DC 儿科哮喘登记处登记的年龄在 2 至 17 岁之间的哮喘儿童。计算了每个 DC 普查区的哮喘相关急诊(ED)就诊和住院的 ARR(结局)。通过使用健康人 2030 年 SDOH 框架选择了五个普查区变量(暴露):教育程度、空房、暴力犯罪、英语水平有限和贫困家庭。
在研究期间,有 4321 名儿童发生了 7515 次 ED 就诊,有 1182 名儿童发生了 1588 次住院治疗。ED 就诊(哮喘儿童每 1000 人 64-728 次)和住院治疗(哮喘儿童每 1000 人 20-240 次)的 ARR 在普查区之间相差 10 倍。在调整分析中,教育程度降低与 ED 就诊的 ARR 显著相关(估计值为 12.1,95%置信区间 [CI] 8.4 至 15.8,P<.001)和住院(估计值 1.2,95%CI 0.2 至 2.2,P=.016)。暴力犯罪与 ED 就诊的 ARR 显著相关(估计值 35.3,95%CI 10.2 至 60.4,P=.006)。
针对 SDOH 的基于地点的干预措施可能是减少哮喘儿童哮喘发病率的机会。