Beck Andrew F, Huang Bin, Wheeler Kathryn, Lawson Nikki R, Kahn Robert S, Riley Carley L
Division of General and Community Pediatrics, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Division of Hospital Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Division of Biostatistics and Epidemiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
J Pediatr. 2017 Nov;190:200-206.e1. doi: 10.1016/j.jpeds.2017.08.007.
To determine whether the Child Opportunity Index (COI), a nationally available measure of relative educational, health/environmental, and social/economic opportunity across census tracts within metropolitan areas, is associated with population- and patient-level asthma morbidity.
This population-based retrospective cohort study was conducted between 2011 and 2013 in a southwest Ohio county. Participants included all children aged 1-16 years with hospitalizations or emergency department visits for asthma or wheezing at a major pediatric hospital. Patients were identified using discharge diagnosis codes and geocoded to their home census tract. The primary population-level outcome was census tract asthma hospitalization rate. The primary patient-level outcome was rehospitalization within 12 months of the index hospitalization. Census tract opportunity was characterized using the COI and its educational, health/environmental, and social/economic domains.
Across 222 in-county census tracts, there were 2539 geocoded hospitalizations. The median asthma-related hospitalization rate was 5.0 per 1000 children per year (IQR, 1.9-8.9). Median hospitalization rates in very low, low, moderate, high, and very high opportunity tracts were 9.1, 7.6, 4.6, 2.1, and 1.8 per 1000, respectively (P < .0001). The social/economic domain had the most variables significantly associated with the outcome at the population level. The adjusted patient-level analyses showed that the COI was not significantly associated with a patient's risk of rehospitalization within 12 months.
The COI was associated with population-level asthma morbidity. The details provided by the COI may inform interventions aimed at increasing opportunity and reducing morbidity across regions.
确定儿童机会指数(COI),一种可在全国范围内获取的衡量大都市地区各普查区相对教育、健康/环境以及社会/经济机会的指标,是否与人群层面和患者层面的哮喘发病率相关。
这项基于人群的回顾性队列研究于2011年至2013年在俄亥俄州西南部的一个县进行。参与者包括在一家大型儿科医院因哮喘或喘息而住院或前往急诊科就诊的所有1至16岁儿童。通过出院诊断代码识别患者,并将其地理编码到其家庭所在的普查区。主要的人群层面结局是普查区哮喘住院率。主要的患者层面结局是首次住院后12个月内的再次住院情况。使用儿童机会指数及其教育、健康/环境和社会/经济领域来描述普查区机会。
在该县的222个普查区中,有2539次地理编码的住院记录。哮喘相关住院率的中位数为每年每1000名儿童5.0例(四分位间距,1.9 - 8.9)。在机会非常低、低、中、高和非常高的普查区,住院率中位数分别为每1000人9.1例、7.6例、4.6例、2.1例和1.8例(P <.0001)。社会/经济领域在人群层面与结局显著相关的变量最多。调整后的患者层面分析表明,儿童机会指数与患者在12个月内再次住院的风险无显著关联。
儿童机会指数与人群层面的哮喘发病率相关。儿童机会指数提供的详细信息可为旨在增加机会和降低各地区发病率的干预措施提供参考。