Venditti F J, Marotta C, Panezai F R, Oldewurtel H A, Regan T J
Miner Electrolyte Metab. 1987;13(1):19-25.
In a prospective study of 34 hospitalized patients with moderate hypophosphatemia as an isolated electrolyte abnormality, the incidence of cardiac arrhythmias has been assessed in the absence of evident cardiac disease. Holter monitoring revealed that those without arrhythmias initially, group A, remained arrhythmia-free on follow-up. Group B (n = 8) had significant arrhythmias (Lown class II or above) and differed at p less than 0.02 from 28 controls. After phosphate replacement the arrhythmias in group B improved or disappeared (p less than 0.02). Thus, in the absence of known causes of cardiac arrhythmia, hypophosphatemia can be associated with significant ventricular ectopic activity.
在一项针对34例住院的中度低磷血症患者（作为孤立的电解质异常）的前瞻性研究中，在无明显心脏病的情况下评估了心律失常的发生率。动态心电图监测显示，最初无心律失常的A组在随访期间仍无心律失常。B组（n = 8）有明显心律失常（洛恩分级II级或以上），与28名对照组相比，p值小于0.02。补充磷酸盐后，B组的心律失常得到改善或消失（p值小于0.02）。因此，在无已知心律失常病因的情况下，低磷血症可能与显著的室性异位活动有关。
