University of Michigan, Ann Arbor, MI.
Section of Vascular Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI.
J Vasc Surg Venous Lymphat Disord. 2022 Nov;10(6):1208-1214. doi: 10.1016/j.jvsv.2022.05.010. Epub 2022 Jul 21.
Phlebectomy of large voluminous varicose veins comes with a risk of substantial blood loss. The purpose of the present study was to investigate the outcomes associated with the use of an adjunct tourniquet during varicose vein surgery of complex and large truncular varicosities.
The prospectively collected registry data included anatomic and outcomes details for patients who presented with complex and large truncular varicosities with a CEAP clinical class of C2, or higher (indicating more serious venous disease) from December 2014 to December 2021. Of all patients, those treated with an adjunct tourniquet for large complex varicosities (largest diameter varicosity ≥1 cm by visual inspection) were selected for analysis. The venous clinical severity scores (VCSSs) and patient-reported outcomes (PROs) were obtained. Additional parameters, including operative time, tourniquet time, and blood loss, were obtained retrospectively via a review of the medical records. Univariate descriptive statistics of the demographic and procedural data were performed pre- and postoperatively, with comparisons performed using the Student two-tailed t test.
The data from 19 patients (22 limbs; 7 women and 12 men) were analyzed. Of the 22 limbs, 11 (50%) had advanced venous disease of C4 or higher preoperatively. A review of the preoperative duplex ultrasound scans confirmed the presence of large varicosities (average, 1.0 ± 0.54 cm; n = 18). All the limbs were treated using radiofrequency ablation of axial reflux and phlebectomy (a combination of powered and stab) under tourniquet control (82%) or phlebectomy under tourniquet control alone (18%). The average tourniquet time was 40 ± 12 minutes, with a median blood loss of 50 mL (interquartile range, 30-100 mL). The average follow-up was 332 ± 422 days after 19 procedures for 16 patients (2 patients moved out of state during the immediate postoperative period and 1 patient was lost to follow-up). Of the patients who completed >3 months of follow-up, 14 limbs experienced improvement in the CEAP class, 5 limbs had no change, and 3 were limbs of patients who moved or were lost to follow-up. The VCSSs significantly improved (8.8 ± 2.8 vs 3.9 ± 1.9; P < .0001). The PROs also improved significantly (16.1 ± 5.0 vs 2.2 ± 2.3; P < .0001).
Tourniquet use in the treatment of varicosities has only been described in the setting of high ligation and stripping. Our data suggest that in the modern era of minimally invasive endovenous treatment of axial reflux and phlebectomy, adjunct tourniquet use during the treatment of large complex varicosities can result in significant improvements in the VCSSs and PROs, with minimal blood loss.
静脉切除术治疗大体积静脉曲张会导致大量失血。本研究旨在探讨在治疗复杂和大隐静脉主干静脉曲张时使用附加止血带的相关结果。
前瞻性收集的登记数据包括 2014 年 12 月至 2021 年 12 月期间就诊的具有复杂和大隐静脉主干静脉曲张(CEAP 临床分级为 C2 或更高,表明静脉疾病更严重)的患者的解剖和结局详细信息。所有患者中,对接受附加止血带治疗的大隐静脉主干静脉曲张(通过肉眼检查,最大直径静脉曲张≥1cm)患者进行了分析。获得静脉临床严重程度评分(VCSS)和患者报告的结局(PRO)。通过回顾病历,回顾性获得手术时间、止血带时间和失血量等其他参数。术前和术后进行人口统计学和程序数据的单变量描述性统计分析,并使用学生双尾 t 检验进行比较。
共分析了 19 例患者(22 条肢体;7 名女性和 12 名男性)的数据。22 条肢体中,术前有 11 条(50%)存在静脉疾病更严重的 C4 或更高分级。术前的双功能超声检查证实存在大隐静脉曲张(平均直径,1.0±0.54cm;n=18)。所有肢体均采用射频消融治疗轴向反流和静脉切除术(动力和穿刺的联合),在止血带控制下(82%)或单独在止血带控制下进行(18%)。平均止血带时间为 40±12 分钟,中位失血量为 50mL(四分位距,30-100mL)。16 例患者共进行了 19 次手术,平均随访 332±422 天(2 例患者在术后即刻搬离州外,1 例患者失访)。在完成>3 个月随访的患者中,14 条肢体的 CEAP 分级得到改善,5 条肢体无变化,3 条肢体为搬离或失访患者的肢体。VCSS 明显改善(8.8±2.8 比 3.9±1.9;P<.0001)。PRO 也明显改善(16.1±5.0 比 2.2±2.3;P<.0001)。
止血带在静脉曲张治疗中的应用仅在高位结扎和剥脱术的背景下有描述。我们的数据表明,在现代微创治疗轴向反流和静脉切除术的时代,在治疗大隐静脉主干静脉曲张时使用附加止血带,可以使 VCSS 和 PRO 显著改善,同时出血量最小。