Laboratory of Emerging Infectious Diseases (LEID), School of Medicine, Pontificia Universidade Católica, Curitiba, Paraná, Brazil; Hospital Universitario Evangélico Mackenzie, Infection Control and Antimicrobial Stewardship Department, Curitiba, Paraná, Brazil.
Laboratory of Emerging Infectious Diseases (LEID), School of Medicine, Pontificia Universidade Católica, Curitiba, Paraná, Brazil; Hospital Universitario Evangélico Mackenzie, Infection Control and Antimicrobial Stewardship Department, Curitiba, Paraná, Brazil.
Am J Infect Control. 2022 Oct;50(10):1182-1184. doi: 10.1016/j.ajic.2022.07.010. Epub 2022 Jul 22.
This was a prospective observational study performed between January and October 2021. Antimicrobial consumption was classified according to AWaRe and expressed as daily defined doses (DDD/1000 patient-days). Watch group antibiotic consumption demonstrated a strong correlation with carbapenem resistance among both clinical and total isolates, but Acinetobacter baumannii resistance did not correlate with antimicrobial consumption. Efforts to reduce antimicrobial consumption are needed; however, prevention and control guidelines are also a cornerstone to better results.
这是一项在 2021 年 1 月至 10 月期间进行的前瞻性观察研究。根据 AWaRe 对抗菌药物的使用进行分类，并表示为每日限定剂量（DDD/1000 患者日）。观察组抗生素的使用与临床和所有分离株的碳青霉烯类耐药均有很强的相关性，但鲍曼不动杆菌的耐药性与抗菌药物的使用无关。需要努力减少抗菌药物的使用；然而，预防和控制指南也是取得更好结果的基石。
