强迫症作为新冠病毒病的首发症状：来自伊朗的系列病例报道
Obsessive compulsive disorder as a presenting symptom of COVID-19: A case-series from Iran.
作者信息
Owji Mahsa, Naser Moghadasi Abdorreza, Gholamian Faezeh, Mousavi Seyed Yaser
机构信息
Multiple Sclerosis Research Center, Neuroscience institute, Tehran University of Medical Sciences, Tehran, Iran.
Department of Psychiatry, Roozbeh Psychiatric Hospital, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
Caspian J Intern Med. 2022;13(Suppl 3):259-263. doi: 10.22088/cjim.13.0.259.
BACKGROUND
Coronavirus disease 2019 (COVID-19) involves different organs and clinical presentations varying from respiratory symptoms to gastrointestinal symptoms and neurological symptoms. Another group of symptoms are psychiatric symptoms and according to a study, 53.8% of participants reported various degrees of these symptoms.
CASE PRESENTATION
In this study, we presented six cases with sudden onset OCD or exacerbation of the previously controlled OCD concomitant with COVID-19 symptoms.
RESULT
Obsessive compulsive symptoms can be the presenting manifestation of COVID-19.
CONCLUSION
The neuropsychiatric manifestations may be resulted from central nervous system (CNS) infiltration, and dysregulation of inflammatory factors autoimmune responses.
背景
2019冠状病毒病（COVID-19）累及不同器官，临床表现多样，从呼吸道症状到胃肠道症状以及神经症状。另一组症状是精神症状，根据一项研究，53.8%的参与者报告有不同程度的这些症状。
病例报告
在本研究中，我们报告了6例突然出现强迫症或既往已得到控制的强迫症加重且伴有COVID-19症状的病例。
结果
强迫症状可能是COVID-19的首发表现。
结论
神经精神表现可能是由中枢神经系统（CNS）浸润以及炎症因子自身免疫反应失调所致。
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