一例合并感染性心内膜炎和新型冠状病毒肺炎的脓毒性肺栓塞罕见病例。
A rare case of septic pulmonary embolism in co-existence with infective endocarditis and COVID-19.
作者信息
Ozdemir Yusuf Emre, Demir Adile Sevde, Ozdemir Meryem Sahin, Mavi Busra, Ozen Can, Karaosmanoglu Hayat Kumbasar
机构信息
Department of Infectious Diseases & Clinical Microbiology, Bakirkoy Dr Sadi Konuk Training Research Hospital, Istanbul, 34140, Turkey.
Department of Infectious Diseases & Clinical Microbiology, Istanbul University - Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, 34093, Turkey.
出版信息
Future Virol. 2022 Jul;0(0). doi: 10.2217/fvl-2022-0029. Epub 2022 Jul 19.
Infective endocarditis (IE) symptoms including fever, fatigue, dyspnea and myalgia are similar in COVID-19 findings. Therefore, the diagnosis of IE may be missed in patients with COVID-19. Co-existence with IE in COVID-19 is rarely reported. However, to our knowledge, only one case of septic pulmonary embolism in COVID-19 and IE was reported. Here, we describe a case of septic embolism due to tricuspid endocarditis caused by intravenous drug use in patients with COVID-19. In this fatal case, the use of prophylactic anticoagulants due to COVID-19 probably caused the tendency to hemorrhagic cerebrovascular complications. Our report emphasizes the complexity of anticoagulant prophylaxis in patients with COVID-19 which may cause hypercoagulopathy in co-existence with IE.
感染性心内膜炎（IE）的症状包括发热、疲劳、呼吸困难和肌痛，与新型冠状病毒肺炎（COVID-19）的表现相似。因此，COVID-19患者可能会漏诊IE。COVID-19合并IE的情况鲜有报道。然而，据我们所知，仅报道过1例COVID-19合并IE及感染性肺栓塞的病例。在此，我们描述1例COVID-19患者因静脉吸毒导致三尖瓣心内膜炎引发感染性栓塞的病例。在这例致命病例中，因COVID-19使用预防性抗凝剂可能导致了出血性脑血管并发症倾向。我们的报告强调了COVID-19患者抗凝预防的复杂性，这可能在合并IE时导致高凝状态。
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