Prinith Nambudumada S, Manjunatha J G, Al-Kahtani Abdullah A, Tighezza Ammar M, Sillanpää Mika
Department of Chemistry, FMKMC College, Constituent College of Mangalore University, Madikeri 571201, Karnataka, India.
Chemistry Department King Saud University, P.O. box 2455, Riyadh 11451, Saudi Arabia.
ACS Omega. 2022 Jun 30;7(28):24679-24687. doi: 10.1021/acsomega.2c02553. eCollection 2022 Jul 19.
Despite the wide range of applications of catechol (CC) in agrochemical, petrochemical, textile, cosmetics, and pharmaceutical industries, its exposure to the environment leads to health issues as it is carcinogenic. This increased the concern over the risk of exposure level of CC in the environment, and monitoring its level has become critical. In this work, we report the fabrication of poly-gibberellic acid-modified carbon paste electrode (PGBAMCPE) to be a simple, viable, and effective electrochemical electrode for the determination of CC. This was synthesized by a simple electropolymerization method by the cyclic voltammetry (CV) technique. The electrodes were characterized by field emission electron microscopy, energy-dispersive X-ray spectroscopy, and electrochemical impedance spectroscopy. Compared to the bare carbon paste electrode, the sensitivity for CC fortified at PGBAMCPE in both CV and differential pulse voltammetry (DPV). We succeeded attaining a lower detection limit of 0.57 μM by the DPV method. The developed electrode was observed to be highly conductive, transducing, stable, and reproducible and was highly selective with anti-interfering properties from the determination of CC with hydroquinone simultaneously. The applicability of the electrode was confirmed from the detection CC in tea and water samples with good recoveries. This substantiates that PGBAMCPE is promising and consistent for the rapid monitoring of CC-contaminated area and clinical diagnosis.
尽管儿茶酚（CC）在农用化学品、石油化工、纺织、化妆品和制药行业有广泛应用，但其接触环境会导致健康问题，因为它具有致癌性。这增加了人们对环境中CC暴露水平风险的担忧，监测其水平变得至关重要。在这项工作中，我们报道了聚赤霉素酸修饰碳糊电极（PGBAMCPE）的制备，它是一种用于测定CC的简单、可行且有效的电化学电极。这是通过循环伏安法（CV）技术采用简单的电聚合方法合成的。通过场发射电子显微镜、能量色散X射线光谱和电化学阻抗谱对电极进行了表征。与裸碳糊电极相比，PGBAMCPE在CV和差分脉冲伏安法（DPV）中对CC强化的灵敏度。我们通过DPV方法成功获得了0.57 μM的较低检测限。观察到所制备的电极具有高导电性、传感性、稳定性和可重复性，并且在同时测定CC和对苯二酚时具有高选择性和抗干扰性能。通过在茶叶和水样中检测CC并具有良好回收率，证实了该电极的适用性。这证实了PGBAMCPE在快速监测CC污染区域和临床诊断方面具有前景且可靠。
