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使用柠檬酸钾的尿路结石患者的禁食及24小时尿液pH值

Fasting and 24-h urine pH in patients with urolithiasis using potassium citrate.

作者信息

da Silva Isabela Bertanholi Leme, Amaro Carmen Petean, Amaro João Luiz, Cunha Natália Baraldi, Callegari Matheus Augusto, Yamamoto Hamilto Akihissa, Guerra Rodrigo, Quitzan Juliany Gomes, Reis Leonardo O, Kawano Paulo Roberto

机构信息

Botucatu School of Medicine and Veterinary Medicine, UNESP-Univ. Estadual Paulista Botucatu-SP, Brazil.

UroScience, University of Campinas, UNICAMP and Pontifical Catholic University of Campinas PUC-Campinas, Campinas-SP, Brazil.

出版信息

Am J Clin Exp Urol. 2022 Jun 15;10(3):188-193. eCollection 2022.

Abstract

PURPOSE

To evaluate the correlation between the pH readings in 24-h urine and the random fasting specimen in patients with urolithiasis using 2 methods.

METHODS

A total of 114 patients with urinary lithiasis using potassium citrate were prospectively analyzed. All patients collected 24-h urine and an additional sample, after nocturnal fasting, collected on the day they brought the 24-h sample at the lab. Two different methods (test strip and digital meter) were used to determine pH values.

RESULTS

The pH analysis using strips in the 24-h urine presented a mean value similar to the one obtained in the fasting sample (6.07 ± 0.74 vs. 6.02 ± 0.82, respectively; P > 0.05). The same behavior was seen considering the readings with a digital pH meter (5.8 ± 0.78 vs. 5.75 ± 0.83; P > 0.05). However, readings conducted in the same specimen with pH meter and test strip were dissonant (P < 0.05), suggesting that the colorimetric method is not reliable in the assessment of urinary pH in this population.

CONCLUSION

pH assessment in a random urinary specimen proved as efficient as the 24-h urine standard method to monitor patients with kidney stones in the use of potassium citrate. Classical test strip analysis is not sensitive enough to evaluate the urine pH in this population and digital pH meter reading is preferred.

摘要

目的

采用两种方法评估肾结石患者24小时尿液pH读数与随机空腹样本之间的相关性。

方法

对114例使用柠檬酸钾的尿石症患者进行前瞻性分析。所有患者收集24小时尿液,并在夜间禁食后,于将24小时样本带到实验室的当天采集额外样本。使用两种不同方法(试纸条和数字式pH计)测定pH值。

结果

24小时尿液试纸条pH分析呈现的平均值与空腹样本中的平均值相似(分别为6.07±0.74和6.02±0.82;P>0.05)。考虑数字式pH计读数时也出现相同情况(5.8±0.78和5.75±0.83;P>0.05)。然而,用pH计和试纸条对同一样本进行的读数不一致(P<0.05),这表明比色法在评估该人群尿液pH时不可靠。

结论

在监测使用柠檬酸钾的肾结石患者时,随机尿样中的pH评估被证明与24小时尿液标准方法一样有效。传统的试纸条分析对评估该人群尿液pH不够敏感,首选数字式pH计读数。

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