Department of Chemistry and Biochemistry, Seton Hall University, 400 South Orange Avenue, South Orange, NJ, 07079, USA.
Org Biomol Chem. 2022 Aug 10;20(31):6188-6192. doi: 10.1039/d2ob00435f.
In this report, we demonstrate that visible light photoactivation of 6-bromo-2-naphthol facilitates the photoacid-catalyzed acetalization of carbonyls with alcohols. We also demonstrate that 2-naphthol when coupled to a photosensitizer provides acetals from electron-deficient aldehydes. In addition, the S excited state p for 6-bromo-2-naphthol in water was determined and shown to have increased excited-state acidity relative to 2-naphthol.
在本报告中，我们证明了 6-溴-2-萘酚的可见光光致活促进了羰基与醇的光酸催化缩醛化反应。我们还证明了，当 2-萘酚与光引发剂结合时，它可以从缺电子的醛提供缩醛。此外，还确定了 6-溴-2-萘酚在水中的 S 激发态 p，并表明其激发态酸度相对于 2-萘酚有所增加。
