Jokić Aleksandar, Lukić Nataša, Pajčin Ivana, Vlajkov Vanja, Dmitrović Selena, Grahovac Jovana
Faculty of Technology Novi Sad, University of Novi Sad, Bulevar cara Lazara 1, 21000 Novi Sad, Serbia.
Membranes (Basel). 2022 Jul 4;12(7):690. doi: 10.3390/membranes12070690.
The use of membrane filtration as a downstream process for microbial biomass harvesting is hampered due to the low permeate flux values achieved during the microfiltration of fermentation broths. Several hydrodynamic methods for increasing permeate flux by creating turbulent flow patterns inside the membrane module are used to overcome this problem. The main goal of this study was to investigate the combined use of a Kenics static mixer and gas sparging during cross-flow microfiltration of IP22 cultivation broth. Optimization of the microfiltration process was performed by using the response surface methodology. It was found that the combined use of a static mixer and gas sparging leads to a considerable increase in the permeate flux, up to the optimum steady-state permeate flux value of 183.42 L·m·h and specific energy consumption of 0.844 kW·h·m. The optimum steady-state permeate flux is almost four times higher, whilst, at the same time, the specific energy consumption is almost three times lower compared to the optimum results achieved using gas sparging alone. The combination of Kenics static mixer and gas sparging during cross-flow microfiltration is a promising technique for the enhancement of steady-state permeate flux with simultaneously decreasing specific energy consumption.
由于在发酵液微滤过程中实现的低渗透通量值，膜过滤作为微生物生物质收获的下游工艺受到阻碍。几种通过在膜组件内部产生湍流模式来增加渗透通量的流体动力学方法被用于克服这个问题。本研究的主要目标是研究在IP22培养液错流微滤过程中Kenics静态混合器和气体鼓泡的联合使用。采用响应面法对微滤过程进行了优化。结果发现，静态混合器和气体鼓泡的联合使用导致渗透通量显著增加，达到最佳稳态渗透通量值183.42 L·m⁻²·h⁻¹，比能耗为0.844 kW·h·m⁻³。与单独使用气体鼓泡获得的最佳结果相比，最佳稳态渗透通量几乎高出四倍，同时比能耗几乎低三倍。在错流微滤过程中Kenics静态混合器和气体鼓泡的联合使用是一种有前景的技术，可提高稳态渗透通量，同时降低比能耗。
