Hagan J C
Ophthalmic Surg. 1987 Apr;18(4):258-61.
The IOLAB AZAR 91Z flexible anterior chamber intraocular lens may have the highest complication rate of any contemporary intraocular implant. Over 40,000 of these implants were inserted in human eyes. The complications of this lens includes a much higher than normal rate of chronic inflammation, cystoid macular edema, glaucoma, hyphema, vitreous hemorrhage, and pseudophakic bullous keratopathy. These complications together constitute the multiple manifestations of the UGH Plus syndrome. These complications tend to increase with time. The failure of the 91Z can be ascribed to problems of design and manufacturing causing excess movement, vaulting, and irritation of ocular tissue. Patients with this implant need to be notified of the high complication rate and the need for frequent follow-up. Most 91Z complications are recurrent or persistent and respond best to removal of the implant. Removal of the 91Z requires special technique to avoid traumatizing the eye. The design, materials, testing, manufacture, and recall of the 91Z needs close study to prevent another such problem prone lens from reaching widespread use.
IOLAB AZAR 91Z可折叠前房人工晶状体可能是所有当代眼内植入物中并发症发生率最高的。超过40000枚这种植入物被植入人眼。该晶状体的并发症包括慢性炎症、黄斑囊样水肿、青光眼、前房积血、玻璃体积血和人工晶状体性大泡性角膜病变的发生率远高于正常水平。这些并发症共同构成了UGH Plus综合征的多种表现。这些并发症往往会随着时间的推移而增加。91Z的失败可归因于设计和制造问题，导致过度移动、拱起以及对眼组织的刺激。需要告知植入这种晶状体的患者其并发症发生率高以及需要频繁随访。大多数91Z并发症是复发性或持续性的，最好的应对方法是取出植入物。取出91Z需要特殊技术以避免损伤眼睛。91Z的设计、材料、测试、制造和召回需要仔细研究，以防止另一种如此容易出现问题的晶状体广泛使用。
