培养的绵羊肺腺瘤肿瘤细胞产生巨噬细胞趋化因子。
Production of a macrophage chemotactic factor by cultured jaagsiekte tumour cells.
作者信息
Myer M S, Verwoerd D W, Garnett H M
出版信息
Onderstepoort J Vet Res. 1987 Mar;54(1):9-15.
PMID:3587935
Abstract
The increase of alveolar macrophages in jaagsiekte sheep lungs is not caused by excessive surfactant production but is due to a chemotactic factor secreted by the tumor cells. This factor has a molecular mass in the region of 13 kilodaltons, is stable at 56 degrees C but labile at 100 degrees C and, being sensitive to proteases, indicates that it is a small protein molecule.
摘要
绵羊肺腺瘤病羊肺中肺泡巨噬细胞数量的增加并非由表面活性剂产生过多所致，而是由肿瘤细胞分泌的一种趋化因子引起的。该因子的分子量在13千道尔顿左右，在56℃时稳定，但在100℃时不稳定，且对蛋白酶敏感，这表明它是一种小蛋白质分子。
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