Schwartz G J, Brion L P, Spitzer A
Pediatr Clin North Am. 1987 Jun;34(3):571-90. doi: 10.1016/s0031-3955(16)36251-4.
The formula GFR = kL/Pcr can be used to estimate GFR in infants, children, and adolescents who have grossly normal body habitus and are in steady-state condition. GFR is expressed in ml/min per 1.73 m2 BSA, L represents body length in cm, Pcr represents plasma creatinine concentration in mg per dl and k is a constant of proportionality that reflects the relationship between urinary creatinine excretion and units of body size. The value of k varies as a function of age and sex being 0.33 in preterm infants, 0.45 in full-term infants, 0.55 in children and adolescent girls, and 0.70 in adolescent boys. The advantages of rapid determination, reasonable accuracy, and the avoidance of urine collection justify the use of this formula in pediatric patients.
公式GFR = kL/Pcr可用于估算身体状况大致正常且处于稳态的婴儿、儿童及青少年的肾小球滤过率（GFR）。GFR的单位是每1.73平方米体表面积的毫升/分钟，L代表身长（厘米），Pcr代表血浆肌酐浓度（毫克/分升），k是反映尿肌酐排泄与身体大小单位之间关系的比例常数。k值随年龄和性别而变化，早产儿为0.33，足月儿为0.45，儿童及青春期女孩为0.55，青春期男孩为0.70。该公式具有快速测定、准确性合理以及无需收集尿液等优点，因此适用于儿科患者。
