School of Physical Education and Sport of Ribeirão Preto, University of São Paulo -EEFERP USP, Ribeirão Preto, SP, Brazil.
Department of Food and Nutrition, School of Pharmaceutical Sciences of Araraquara, São Paulo State University - FCF UNESP, Araraquara, SP, Brazil.
Adv Exp Med Biol. 2022;1370:279-289. doi: 10.1007/978-3-030-93337-1_27.
Taurine has been investigated as a possible strategy for the treatment of obesity. The benefits of taurine supplementation and the importance of adipose tissue to the whole-body energy metabolism are undeniable; however, the impact of the association of taurine and exercise on adipose tissue dynamics remains unclear, especially in the context of obesity. The present investigation sought to explore the effects of taurine supplementation associated with physical exercise as an excellent strategy for treating and preventing obesity. We highlighted the main studies that support the effects of taurine associated with exercise on the modulation of energy and lipid metabolism and also its impacts on the adipose tissue metabolism and morphology in obese individuals and obese animal models, suggesting taurine as a promising strategy to combat obesity. However, more investigations are necessary to elucidate the safe and effective dose, the mechanisms, and the potential effects of taurine supplementation associated with exercise in the adipose tissue as a therapeutic strategy for preventing and treating obesity.
牛磺酸已被研究作为治疗肥胖的一种可能策略。牛磺酸补充的益处以及脂肪组织对全身能量代谢的重要性是不可否认的；然而，牛磺酸与运动的结合对脂肪组织动力学的影响仍不清楚，特别是在肥胖的背景下。本研究旨在探讨牛磺酸补充与体育锻炼相结合作为治疗和预防肥胖的一种极好策略的效果。我们强调了支持牛磺酸与运动相结合对能量和脂质代谢调节的主要研究，以及它对肥胖个体和肥胖动物模型脂肪组织代谢和形态的影响，表明牛磺酸是一种有前途的对抗肥胖的策略。然而，还需要更多的研究来阐明牛磺酸补充与运动相结合在脂肪组织中作为预防和治疗肥胖的治疗策略的安全性和有效性剂量、机制和潜在影响。
