Comprehensive Serial Treatment of Treacher Collins Syndrome.

OBJECTIVE

To discuss and summarize the comprehensive serial surgical treatment of Treacher Collins syndrome.

MATERIALS AND METHODS

From September 2012 to January 2020, 12 patients with Treacher Collins syndrome were treated by autologous fat graft, mandibular distraction osteogenesis, orbitozygomatic reconstruction with calvarial external lamina, orthognathic surgery combined with postoperative orthodontics, transplantation of upper eyelid orbicularis myocutaneous flap, lateral canthal ligament reduction, and other methods. The authors evaluated the postoperative improvement, summarized experiences, and reviewed literatures about the comprehensive serial treatment of Treacher Collins syndrome.

RESULTS

All patients showed significant improvement in appearance and function, and no complications were found during the follow-up period of 5 months to 3 years.

CONCLUSIONS

The deformities of Treacher Collins syndrome involves multiple craniofacial region, and only by formulating comprehensive serial treatment strategies according to the malformation characteristics of different patients can the best effect be achieved.