Giammalva Giuseppe Roberto, Dell'Aglio Letizia, Guarrera Brando, Baro Valentina, Calvanese Leonardo, Schiavo Gloria, Mantovani Giulia, Rinaldi Valentina, Iacopino Domenico Gerardo, Causin Francesco, Nicolai Piero, Ferrari Marco, Denaro Luca
Unit of Neurosurgery, Post Graduate Residency Program in Neurosurgery, Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, 90100 Palermo, Italy.
Academic Neurosurgery, Department of Neurosciences DNS, University of Padua, 35128 Padua, Italy.
Brain Sci. 2022 Jul 13;12(7):916. doi: 10.3390/brainsci12070916.
Osteoid osteoma (OO) is a primary benign tumor that accounts for up to 3% of all bone tumors. The cervical spine is less affected by OOs, and very few cases of C2 OOs have been reported in the literature, both in adults and children. Surgery may be required in case of functional torticollis, stiffness, and reduced range of motion (ROM) due to cervical OOs refractory to medical therapy. Several posterior and anterior surgical techniques have been described to remove C2 OOs. In particular, anterior approaches to the cervical spine represent the most used surgical route for treating C2 OOs. We describe the first case of OO of the odontoid process removed through a transnasal endoscopic approach with the aid of neuronavigation in a 6-year-old child. No intraoperative complications occurred, and the post-operative course was uneventful. The patient had immediate relief of neck pain and remained pain-free throughout the follow-up period, with complete functional recovery of the neck range of motion (ROM). In this case, based on the favorable anatomy, the transnasal endoscopic approach represented a valuable strategy for the complete removal of an anterior C2 OO without the need for further vertebral fixation since the preservation of ligaments and paravertebral soft tissue.
骨样骨瘤(OO)是一种原发性良性肿瘤,占所有骨肿瘤的比例高达3%。颈椎受骨样骨瘤影响较少,无论是成人还是儿童,文献中报道的C2骨样骨瘤病例都非常少。对于因药物治疗无效的颈椎骨样骨瘤导致的功能性斜颈、僵硬和活动范围(ROM)减小的情况,可能需要进行手术。已经描述了几种后路和前路手术技术来切除C2骨样骨瘤。特别是,颈椎前路手术是治疗C2骨样骨瘤最常用的手术途径。我们描述了第一例在一名6岁儿童中,借助神经导航通过经鼻内镜手术切除齿状突骨样骨瘤的病例。术中未发生并发症,术后过程顺利。患者颈部疼痛立即缓解,在整个随访期间均无疼痛,颈部活动范围(ROM)完全恢复功能。在该病例中,基于有利的解剖结构,经鼻内镜手术是一种有价值的策略,可在保留韧带和椎旁软组织的情况下,无需进一步椎体固定即可完全切除C2前部骨样骨瘤。