Neștianu Erick George, Brădeanu Cristina Guramba, Alexandru Dragoș Ovidiu, Vlădăreanu Radu
Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 030167 Bucharest, Romania.
Affidea Medical Center, 022238 Bucharest, Romania.
Diagnostics (Basel). 2022 Jul 17;12(7):1733. doi: 10.3390/diagnostics12071733.
This is a retrospective study investigating the relationship between ultrasound and magnetic resonance imaging (MRI) examinations in congenital diaphragmatic hernia (CDH). CDH is a rare cause of pulmonary hypoplasia that increases the mortality and morbidity of patients. Inclusion criteria were: patients diagnosed with CDH who underwent MRI examination after the second-trimester morphology ultrasound confirmed the presence of CDH. The patients came from three university hospitals in Bucharest, Romania. A total of 22 patients were included in the study after applying the exclusion criteria. By analyzing the total lung volume (TLV) using MRI, and the lung to head ratio (LHR) calculated using MRI and ultrasound, we observed that LHR can severely underestimate the severity of the pulmonary hypoplasia, even showing values close to normal in some cases. This also proves to be statistically relevant if we eliminate certain extreme values. We found significant correlations between the LHR percentage and herniated organs, such as the left and right liver lobes and gallbladder. MRI also provided additional insights, indicating the presence of pericarditis or pleurisy. We wish to underline the necessity of MRI follow-up in all cases of CDH, as the accurate measurement of the TLV is important for future treatment and therapeutic strategy.
这是一项回顾性研究,旨在调查先天性膈疝(CDH)患者超声检查与磁共振成像(MRI)检查之间的关系。CDH是肺发育不全的罕见病因,会增加患者的死亡率和发病率。纳入标准为:在孕中期形态超声确认存在CDH后接受MRI检查且被诊断为CDH的患者。这些患者来自罗马尼亚布加勒斯特的三家大学医院。在应用排除标准后,共有22名患者纳入本研究。通过使用MRI分析总肺容积(TLV),以及使用MRI和超声计算肺头比(LHR),我们观察到LHR可能会严重低估肺发育不全的严重程度,甚至在某些情况下显示的值接近正常。如果我们剔除某些极端值,这在统计学上也具有相关性。我们发现LHR百分比与疝出器官(如左右肝叶和胆囊)之间存在显著相关性。MRI还提供了额外的信息,表明存在心包炎或胸膜炎。我们希望强调在所有CDH病例中进行MRI随访的必要性,因为准确测量TLV对未来的治疗和治疗策略很重要。