Levy A B, Dixon K N, Schmidt H
Psychiatry Res. 1987 Mar;20(3):189-97. doi: 10.1016/0165-1781(87)90078-3.
Several recent investigations have suggested that neurobiological similarities may exist between patients with eating disorders and those with depression. We performed polysomnograms for two consecutive nights on nine bulimic and six anorectic patients who had no concomitant diagnosis of endogenous depression. The rapid eye movement (REM) latency, REM density, and delta sleep of these subjects on night 2 were compared to those of 10 healthy controls of similar ages. Contrary to reports of shortened REM latency and increased REM density in depressed patients, we did not find significant REM differences between eating disorder patients without endogenous depression and healthy control subjects. Low weight anorectics did appear to have less delta sleep than did controls. These findings do not support the contention that eating disorders are variants of affective disorders.
最近的几项研究表明，饮食失调患者与抑郁症患者之间可能存在神经生物学上的相似性。我们对9名贪食症患者和6名厌食症患者连续两晚进行了多导睡眠图监测，这些患者均未同时被诊断为内源性抑郁症。将这些受试者第二晚的快速眼动（REM）潜伏期、REM密度和慢波睡眠与10名年龄相仿的健康对照者进行了比较。与抑郁症患者REM潜伏期缩短和REM密度增加的报道相反，我们未发现无内源性抑郁症的饮食失调患者与健康对照者之间存在显著的REM差异。体重过轻的厌食症患者的慢波睡眠似乎确实比对照组少。这些发现不支持饮食失调是情感障碍变体的观点。
