Abe Yuriko, Tonouchi Ryousuke, Hara Mitsuhiko, Okada Tomoo, Jego Eric H, Taniguchi Tetsuya, Koshinaga Tsugumichi, Morioka Ichiro
Division of Medical Education, Nihon University School of Medicine, Tokyo 173-8610, Japan.
Medical Education Center, Nihon University School of Medicine, Tokyo 173-8610, Japan.
J Clin Med. 2022 Jul 17;11(14):4148. doi: 10.3390/jcm11144148.
Abdominal bioelectrical impedance analysis (aBIA) has been in use to measure visceral fat area (VFA) in adults. Accurately measuring visceral fat using aBIA in children is challenging. Forty-six school-aged Japanese children aged 6-17 years (25 boys and 21 girls) were included in this study. All were measured, and their VFA obtained using aBIA (VFA-aBIA) and abdominal computed tomography (CT) (VFA-CT) were compared. VFA-aBIA was corrected using the Passing-Bablok method (corrected VFA-aBIA). The relationships between corrected VFA-aBIA and obesity-related clinical factors were analyzed, including non-alcoholic fatty liver disease (NAFLD) and serum leptin and adiponectin levels. Boys had higher VFA-CT than girls ( = 0.042), although no significant differences were found in their waist circumference, waist-to-height ratio, and body mass index. The corrected VFA-aBIA using y = 9.600 + 0.3825x (boys) and y = 7.607 + 0.3661x (girls) correlated with VFA-CT in both boys and girls. The corrected VFA-aBIA in patients with NAFLD was higher than that in those without NAFLD. Serum leptin and adiponectin levels were positively and negatively correlated with corrected VFA-aBIA, respectively. In conclusion, corrected VFA-aBIA was clearly correlated with VFA-CT and was related to NAFLD and serum leptin and adiponectin levels in school-aged Japanese children.
腹部生物电阻抗分析(aBIA)已被用于测量成年人的内脏脂肪面积(VFA)。使用aBIA准确测量儿童的内脏脂肪具有挑战性。本研究纳入了46名6至17岁的日本学龄儿童(25名男孩和21名女孩)。对所有儿童进行了测量,并比较了使用aBIA获得的VFA(VFA-aBIA)和腹部计算机断层扫描(CT)获得的VFA(VFA-CT)。使用Passing-Bablok方法对VFA-aBIA进行校正(校正后的VFA-aBIA)。分析了校正后的VFA-aBIA与肥胖相关临床因素之间的关系,包括非酒精性脂肪性肝病(NAFLD)以及血清瘦素和脂联素水平。男孩的VFA-CT高于女孩(P = 0.042),尽管他们的腰围、腰高比和体重指数没有显著差异。使用y = 9.600 + 0.3825x(男孩)和y = 7.607 + 0.3661x(女孩)校正后的VFA-aBIA与男孩和女孩的VFA-CT均相关。NAFLD患者校正后的VFA-aBIA高于无NAFLD的患者。血清瘦素和脂联素水平分别与校正后的VFA-aBIA呈正相关和负相关。总之,校正后的VFA-aBIA与VFA-CT明显相关,并且与日本学龄儿童的NAFLD以及血清瘦素和脂联素水平有关。