Moser R P, Vinh T N, Ros P R, Smirniotopoulos J G, Madewell J E, Berrey B H
Radiology. 1987 Jul;164(1):211-4. doi: 10.1148/radiology.164.1.3588906.
A study was done of 13 cases of biopsy-proved Paget disease in which the disease involved the anterior tibial tubercle with extension into the metaphysis and diaphysis, but without apparent involvement of the proximal tibial epiphysis. Case data were obtained from archives containing more than 350 cases of Paget disease. Age, sex, symptoms, serum alkaline phosphatase level, and histologic and radiographic appearance of the lesions were evaluated. Patients were young at clinical presentation, averaging 36 years of age. In five of six patients the serum alkaline phosphatase level was normal. The proximal extent of the disease was the anterior tibial tubercle rather than the proximal epiphysis. Radiographic patterns ranged from predominantly lytic to mixed lytic and blastic to predominantly blastic, and the lesion was marginated by a flame-shaped configuration. The radiographic appearance of Paget disease of the anterior tibial tubercle is characteristic and should be sufficient to suggest the diagnosis and preclude biopsy.
对13例经活检证实的佩吉特病患者进行了一项研究，这些患者的疾病累及胫骨前结节，并延伸至干骺端和骨干，但胫骨近端骨骺未明显受累。病例数据来自包含350多例佩吉特病病例的档案。对患者的年龄、性别、症状、血清碱性磷酸酶水平以及病变的组织学和影像学表现进行了评估。患者临床表现时年龄较轻，平均36岁。六名患者中有五名血清碱性磷酸酶水平正常。疾病的近端范围是胫骨前结节而非近端骨骺。影像学表现从以溶骨性为主到溶骨性与成骨性混合再到以成骨性为主，病变以火焰状形态为边界。胫骨前结节佩吉特病的影像学表现具有特征性，应足以提示诊断并避免活检。
