营养与肠道-大脑通路对帕金森病发病的影响。
Nutrition and Gut-Brain Pathways Impacting the Onset of Parkinson's Disease.
机构信息
Department of Decision Neuroscience and Nutrition, German Institute of Human Nutrition (DIfE), Potsdam Rehbrücke, 14558 Nuthetal, Germany.
Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Neuroscience Research Center, 10117 Berlin, Germany.
出版信息
Nutrients. 2022 Jul 6;14(14):2781. doi: 10.3390/nu14142781.
An emerging body of literature suggests that long-term gut inflammation may be a silent driver of Parkinson's disease (PD) pathogenesis. Importantly, specific nutritive patterns might improve gut health for PD risk reduction. Here, we review the current literature on the nutritive patterns and inflammatory markers as a predictor for early detection of PD. This knowledge might be used to foster the detection of early nutritive patterns and preclinical biomarkers to potentially alter PD development and progression.
越来越多的文献表明，长期的肠道炎症可能是帕金森病（PD）发病机制的一个潜在驱动因素。重要的是，特定的营养模式可能有助于改善肠道健康，从而降低 PD 的发病风险。在这里，我们回顾了目前关于营养模式和炎症标志物作为 PD 早期检测预测因子的文献。这些知识可以用来促进早期营养模式和临床前生物标志物的检测，从而有可能改变 PD 的发展和进程。
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