Emhmed Ali Saad, Bhakta Avinash, Bautista Robert-Marlo, Sherif Ahmed, Frandah Wesam
Department of Medicine, University of Kentucky, Lexington, KY, USA.
Transl Gastroenterol Hepatol. 2022 Jul 25;7:32. doi: 10.21037/tgh.2020.03.06. eCollection 2022.
Benign strictures of the colon and rectum affect a sizable portion of patients who have an underlying inflammatory disease or who have undergone recent surgery. Etiologies include inflammatory bowel disease (IBD), post-surgical ischemia, anastomotic strictures, non-steroidal anti-inflammatory drugs (NSAIDs), and complicated diverticulitis. Refractory colorectal strictures are very difficult to manage and often require repeated and different treatment options. We report a novel technique using argon plasma coagulation (APC) with endoscopic balloon dilation (EBD) as a safe and effective treatment modality for refractory benign colorectal strictures. Four patients with symptomatic benign colorectal strictures were referred for endoscopic treatment. In all cases (two females and two males; average age 62 years), the endoscopic and radiographic assessment showed significant strictures (diameter, 4-13 mm). The stricture was secondary to Crohn's disease in one patient and anastomotic strictures in the other three patients. Endoscopic stricturotomy through fulguration and tissue destruction using argon plasma at 1.5 liters/minute, effect 2, and 40 watts was performed, followed by EBD. All patients were treated by one advanced endoscopist. The primary outcomes were the efficiency and safety of endoscopic stricturotomy with pulsed argon plasma and balloon dilation. The resolution of stricture was achieved in all patients. No complications were reported. We believe that combined APC with EBD is a safe and effective technique in the treatment of benign colonic stricture.
结肠和直肠的良性狭窄影响着相当一部分患有潜在炎症性疾病或近期接受过手术的患者。病因包括炎症性肠病(IBD)、术后缺血、吻合口狭窄、非甾体抗炎药(NSAIDs)以及复杂性憩室炎。难治性结直肠狭窄很难处理,通常需要反复采用不同的治疗方案。我们报告了一种新技术,即使用氩等离子体凝固术(APC)联合内镜球囊扩张术(EBD)作为治疗难治性良性结直肠狭窄的一种安全有效的治疗方式。4例有症状的良性结直肠狭窄患者被转诊接受内镜治疗。在所有病例中(2名女性和2名男性;平均年龄62岁),内镜和影像学评估显示存在明显狭窄(直径4 - 13毫米)。1例患者的狭窄继发于克罗恩病,其他3例患者的狭窄为吻合口狭窄。使用氩等离子体以每分钟1.5升、效果2和40瓦进行电凝和组织破坏,随后进行内镜下狭窄切开术,接着进行EBD。所有患者均由一名资深内镜医师治疗。主要观察指标是脉冲氩等离子体联合球囊扩张进行内镜下狭窄切开术的有效性和安全性。所有患者的狭窄均得到缓解。未报告并发症。我们认为,APC联合EBD是治疗良性结肠狭窄的一种安全有效的技术。