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激光治疗女性生殖泌尿系统综合征:科学影响报告第 72 号(2022 年 7 月):科学影响报告第 72 号(2022 年 7 月)。

Laser treatment for genitourinary syndrome of menopause: Scientific Impact Paper No. 72 (July 2022): Scientific Impact Paper No. 72 (July 2022).

出版信息

BJOG. 2022 Nov;129(12):e89-e94. doi: 10.1111/1471-0528.17195. Epub 2022 Jul 27.

Abstract

Genitourinary syndrome of menopause (GSM) is the term used to describe the group of symptoms including vaginal pain, vaginal dryness, itching, pain during sexual intercourse and fragile vaginal tissues as well as urinary symptoms including urinary frequency, urgency, incontinence, blood in the urine (haematuria) and recurrent urinary tract infections that occur due to a lack of the hormone estrogen. These symptoms can have a significant negative impact on psychosexual issues, sexual function and quality of life in postmenopausal women. Traditionally women have been treated with vaginal lubricants, vaginal moisturisers or low-dose vaginal estrogens. Lasers have been used in the cosmetic industry for collagen remodelling and repair of the skin. Therefore, it has been suggested that laser therapy may be used on the vagina as an alternative treatment for GSM. A review of all the published studies assessing the safety and efficacy of laser therapy for GSM have shown promising beneficial results. The majority of studies to date have been small, short-term, observational studies. However, there are randomised controlled trials underway. Laser treatment may be beneficial for the symptoms of GSM but until more robust evidence is available it should not be adopted into widespread practice, and should be used as part of a research study only.

摘要

绝经后生殖泌尿系统综合征(GSM)是一个术语,用于描述一组症状,包括阴道疼痛、阴道干燥、瘙痒、性交疼痛和脆弱的阴道组织,以及泌尿系统症状,包括尿频、尿急、失禁、血尿(血尿)和复发性尿路感染,这些症状是由于缺乏激素雌激素引起的。这些症状会对绝经后妇女的心理性问题、性功能和生活质量产生重大负面影响。传统上,女性使用阴道润滑剂、阴道保湿剂或低剂量阴道雌激素进行治疗。激光已在美容行业中用于胶原蛋白重塑和皮肤修复。因此,有人提出激光疗法可用于阴道,作为 GSM 的替代治疗方法。对所有评估激光治疗 GSM 的安全性和有效性的已发表研究进行的综述显示出有希望的有益结果。迄今为止,大多数研究都是小型、短期、观察性研究。但是,正在进行随机对照试验。激光治疗可能对 GSM 的症状有益,但在有更可靠的证据之前,不应将其广泛应用于临床实践,而应仅作为研究的一部分使用。

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