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急性卡马西平中毒

Acute Carbamazepine Intoxication.

作者信息

Gallego María Dolores Calabria, García Mónica Alañá

机构信息

IBSAL, Institute for Biomedical Research of Salamanca, 37007 Salamanca, Spain.

Neurology Department, Universitary Hospital of Salamanca, 37007 Salamanca, Spain.

出版信息

Neurol Int. 2022 Jul 22;14(3):614-618. doi: 10.3390/neurolint14030049.

Abstract

Carbamazepine is an anticonvulsant drug with multiple mechanisms of action, which condition the presence of a characteristic clinical picture after the overingestion of the drug. We expose a case report about a patient who, in the context of an attempted suicide, presented acute intoxication by benzodiazepines and carbamazepine, presenting the characteristic clinical picture of fluctuations in the level of consciousness, even presenting gaze deconjugation, almost unreactive coma and generalized hypotonia.

摘要

卡马西平是一种具有多种作用机制的抗惊厥药物,药物过量摄入后会出现典型的临床表现。我们报告一例患者,该患者在自杀未遂时,出现苯二氮䓬类药物和卡马西平急性中毒,表现出意识水平波动的典型临床症状,甚至出现眼球运动分离、几乎无反应性昏迷和全身肌张力减退。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f01b/9331306/be0b1915979f/neurolint-14-00049-g001.jpg

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