Tiberghien P, Rosenbaum A, Schaal J P, Flesch M, Carbillet J P, Colette C, Leconte des Floris R
Rev Fr Gynecol Obstet. 1987 Mar;82(3):185-92.
Mammary localizations of non-hodgkinian malignant lymphomas (NHML) are rare. They occur in three different contexts: isolated tumor of the primary mammary lymphoma, initial "first manifestation" tumor of a diffuse lymphomatous disease, or else a mammary tumor occurring during the course of a known NHML. Four cases of mammary localization of NHML are reported. A review of the literature permits to bring out the following characteristics: probable etiological role of pregnancy, clinical picture of one or several masses, uni or bilateral, evoluting rapidly, and frequently associated to inflammatory signs; false benign aspect on mammograms. Histological examination associated with a strict evaluation of the extension is fundamental in order to determine therapy and prognosis. These two factors have been considerably modified in the past two decades as it is the case for all NHML. Chemotherapy occupies an essential place in the treatment. Mammary localization of NHML is first of all a lymphomatous disease, which is often a diffuse disease before becoming a breast disease.
非霍奇金恶性淋巴瘤（NHML）的乳腺定位罕见。它们出现在三种不同情况下：原发性乳腺淋巴瘤的孤立肿瘤、弥漫性淋巴瘤疾病的初始“首发表现”肿瘤，或者在已知NHML病程中出现的乳腺肿瘤。本文报告了4例NHML乳腺定位病例。文献综述显示出以下特征：妊娠可能的病因作用、一个或多个肿块的临床表现，单侧或双侧，发展迅速，且常伴有炎症体征；乳房X光片上的假良性表现。组织学检查结合对病变范围的严格评估对于确定治疗和预后至关重要。在过去二十年中，这两个因素与所有NHML一样有了很大改变。化疗在治疗中占据重要地位。NHML的乳腺定位首先是一种淋巴瘤疾病，在成为乳腺疾病之前通常是一种弥漫性疾病。
