Bužančić Iva, Ortner Hadžiabdić Maja
Faculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, 10 000 Zagreb, Croatia.
City Pharmacies Zagreb, Kralja Držislava 6, 10 000 Zagreb, Croatia.
Pharmacy (Basel). 2022 Jul 1;10(4):76. doi: 10.3390/pharmacy10040076.
Successful implementation of deprescribing requires exploring healthcare professionals’ opinions, preferences, and attitudes towards deprescribing. The aim of this study was to develop and validate the questionnaire exploring healthcare providers’ opinions preferences and attitudes towards deprescribing (CHOPPED questionnaire). This was a cross-sectional on-line survey. A comprehensive 58-item questionnaire, in two versions (for pharmacists and physicians), was developed through an extensive literature review and interviews with experts. The questionnaire was validated, and its reliability was assessed through data collected from 356 pharmacists and 109 physicians. Exploratory factor analysis was performed, and 37- and 35-item questionnaires were developed. Ten factors were identified: knowledge, awareness, patient barriers and facilitators, competencies barriers and facilitators, collaboration barriers and facilitators, and healthcare system barriers and facilitators. The CHOPPED tool has satisfactory face, content (CVR > 0.62) (content validity ratio), construct, and criterion validity. The reliability statistics of all factors in both versions was acceptable with Cronbach’s alpha > 0.6. Test−retest reliability analysis showed that gamma rank correlations of total factor scores were strong and very strong (between 0.519 and 0.938). The CHOPPED tool can be used as a valid and reliable tool to explore healthcare providers’ opinions and attitudes toward discontinuing medications in the primary care setting in Croatia.
成功实施减药需要探究医疗保健专业人员对减药的看法、偏好和态度。本研究的目的是开发并验证一份探究医疗保健提供者对减药的看法、偏好和态度的问卷（CHOPPED问卷）。这是一项横断面在线调查。通过广泛的文献综述和专家访谈，开发了一份包含58个条目的综合问卷，有两个版本（分别针对药剂师和医生）。该问卷经过验证，并通过收集356名药剂师和109名医生的数据对其信度进行了评估。进行了探索性因素分析，得出了分别包含37个和35个条目的问卷。确定了十个因素：知识、意识、患者障碍与促进因素、能力障碍与促进因素、协作障碍与促进因素以及医疗保健系统障碍与促进因素。CHOPPED工具具有令人满意的表面效度、内容效度（CVR>0.62）（内容效度比）、结构效度和效标效度。两个版本中所有因素的信度统计结果均可接受，Cronbach's alpha>0.6。重测信度分析表明，总因素得分的伽马等级相关性很强（在0.519至0.938之间）。CHOPPED工具可作为一种有效且可靠的工具，用于探究克罗地亚初级保健环境中医疗保健提供者对停药的看法和态度。
