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荧光素衍生物固定化光学水凝胶:制备及其在检测羟基自由基中的应用

Fluorescein Derivative Immobilized Optical Hydrogels: Fabrication and Its Application for Detection of HO.

作者信息

Qu Zixiang, Zhang Demeng, Wang Chuane, Tian Sheng, Deng Yunlong, Qin Dawei, Duan Hongdong

机构信息

School of Chemistry and Chemical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China.

State Key Laboratory of Bioactive Seaweed Substances, Qingdao Bright Moon Seaweed Group Co., Ltd., Qingdao 266400, China.

出版信息

Polymers (Basel). 2022 Jul 26;14(15):3005. doi: 10.3390/polym14153005.

Abstract

A novel fluorescein-based probe was developed for detecting HO. Modified by 2-Bromomethylphenylboronic acid pinacol ester, is a Fluorescein derivative with eminent photostability and remarkable HO sensitivity and selectivity. was utilized to synthesize hydrogel sensors in the manner of guest-host interaction by taking advantage of its aforementioned features. The hydrogel sensor can be used to detect HO effectively in both flowing and static water environments with satisfactory performance. It is expected that this application may open a new page to develop a neoteric fluorescent property analysis method aiming at HO detection.

摘要

一种新型的基于荧光素的探针被开发用于检测羟基自由基(HO)。经2-溴甲基苯硼酸频哪醇酯修饰,是一种具有卓越光稳定性以及显著的羟基自由基敏感性和选择性的荧光素衍生物。利用其上述特性,通过客体-主体相互作用的方式将其用于合成水凝胶传感器。该水凝胶传感器能够在流动和静态水环境中有效地检测羟基自由基,性能令人满意。预计这一应用可能为开发一种针对羟基自由基检测的新型荧光特性分析方法翻开新的篇章。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec6/9332226/2f5b00f9d976/polymers-14-03005-sch001.jpg

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