Department of Chemistry, COMSATS University Islamabad, Abbottabad Campus, University Road, Abbottabad 22060, Pakistan.
Department of Chemistry, College of Science, University of Bahrain, Sakhir 32038, Bahrain.
Analyst. 2022 Aug 22;147(17):3885-3893. doi: 10.1039/d2an00937d.
Apart from environmental implications, the extreme toxicity of cyanide can lead to sudden human death upon prolonged exposure to it. Hence, rapid and low-level on-site detection of cyanide has earned paramount significance in the present era. Therefore, an AIEE active and piezofluorochromic Schiff base (probe 2) was synthesized which exhibited highly selective fluorescence enhancement based nanoscale (LOD; 6.17 nM) detection of CN. The interaction mode was attributed to the deprotonation of the probe by the cyanide that was confirmed through H NMR titration, pH, theoretical studies, and switchable fluorescence response upon the addition of HCl. Advantageously, probe 2 displayed solid and vapor phase recognition of cyanide which is the first of its kind as far as we know. The excellent sensing potential of the probe was satisfactorily applied for the detection of cyanide in food, natural soil, and industrial wastewater. Additionally, probe 2 showed an immediate colorimetric response towards cyanide which was favorably integrated through a smartphone. Finally, the switchable fluorescence response of the probe was used to design an INHIBIT logic gate. Therefore, the multifunctional probe 2 displayed excellent practical potential for cyanide detection which was the ultimate goal of our work.
除了环境影响外，氰化物的极端毒性会导致人类在长时间暴露于其中后突然死亡。因此，在当今时代，快速、低水平的现场氰化物检测变得至关重要。因此，合成了一种 AIEE 活性和压致荧光变色席夫碱（探针 2），它对 CN 表现出高度选择性的荧光增强纳米级（LOD；6.17 nM）检测。相互作用模式归因于氰化物使探针去质子化，这通过 H NMR 滴定、pH 值、理论研究以及添加 HCl 时的可切换荧光响应得到证实。有利的是，探针 2 显示出对氰化物的固相与气相识别，就我们所知，这是首例。探针的优异传感潜力在食品、天然土壤和工业废水中的氰化物检测中得到了令人满意的应用。此外，探针 2 对氰化物表现出即时的比色响应，可通过智能手机进行有利的集成。最后，探针的可切换荧光响应用于设计 INHIBIT 逻辑门。因此，多功能探针 2 显示出用于氰化物检测的优异实际潜力，这是我们工作的最终目标。
