• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

From resveratrol to ISIDE11: how to activate SIRT1 and improve endothelial function? New therapeutic insights for methylenetetrahydrofolate reductase deficiency.

作者信息

Jankauskas Stanislovas S, Mone Pasquale, Santulli Gaetano

机构信息

Department of Medicine, Wilf Family Cardiovascular Research Institute, Institute for Neuroimmunology and Inflammation (INI), Einstein Institute for Aging Research, 1300 Morris Park Avenue, New York, NY, 10461, USA.

Department of Molecular Pharmacology, Einstein-Mount Sinai Diabetes Research Center (ES-DRC), Albert Einstein College of Medicine, Fleischer Institute for Diabetes and Metabolism (FIDAM), Albert Einstein College of Medicine, New York, NY, USA.

出版信息

Cell Mol Life Sci. 2022 Jul 27;79(8):451. doi: 10.1007/s00018-022-04484-y.

DOI:10.1007/s00018-022-04484-y
PMID:35895130
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9843588/
Abstract
摘要

相似文献

1
From resveratrol to ISIDE11: how to activate SIRT1 and improve endothelial function? New therapeutic insights for methylenetetrahydrofolate reductase deficiency.从白藜芦醇到ISIDE11：如何激活SIRT1并改善内皮功能？亚甲基四氢叶酸还原酶缺乏症的新治疗见解。
Cell Mol Life Sci. 2022 Jul 27;79(8):451. doi: 10.1007/s00018-022-04484-y.
2
SIRT1 pharmacological activation rescues vascular dysfunction and prevents thrombosis in MTHFR deficiency.SIRT1 药理学激活可挽救 MTHFR 缺乏症中的血管功能障碍并预防血栓形成。
Cell Mol Life Sci. 2022 Jul 11;79(8):410. doi: 10.1007/s00018-022-04429-5.
3
Methylenetetrahydrofolate reductase deficiency (homocystinuria type II) as a rare cause of rapidly progressive tetraspasticity and psychosis in a previously healthy adult.亚甲基四氢叶酸还原酶缺乏症（II型同型胱氨酸尿症）是一名既往健康的成年人快速进展性四肢痉挛和精神病的罕见病因。
J Neurol. 2008 Nov;255(11):1845-6. doi: 10.1007/s00415-008-0043-3. Epub 2008 Oct 7.
4
Adult-onset severe methylenetetrahydrofolate reductase deficiency characterized by reversible spastic paraplegia with a novel mutation.以可逆性痉挛性截瘫为特征的成人型严重亚甲基四氢叶酸还原酶缺乏症伴新突变。
Neurol Sci. 2016 Oct;37(10):1735-7. doi: 10.1007/s10072-016-2580-3. Epub 2016 Apr 27.
5
Methylenetetrahydrofolate Reductase Deficiency as a Cause of Treatable Adult-onset Leukoencephalopathy and Myelopathy.亚甲基四氢叶酸还原酶缺乏症作为成人起病的可治疗性白质脑病和脊髓病的病因
Clin Neuroradiol. 2021 Mar;31(1):277-281. doi: 10.1007/s00062-020-00947-6. Epub 2020 Sep 3.
6
[Methylenetetrahydrofolate Reductase deficiency and anesthesia: importance of a detailed preoperative evaluation].[亚甲基四氢叶酸还原酶缺乏与麻醉：详细术前评估的重要性]
Braz J Anesthesiol. 2019 Nov-Dec;69(6):637-638. doi: 10.1016/j.bjan.2019.05.002. Epub 2019 Nov 30.
7
Late-onset 5,10-methylenetetrahydrofolate reductase deficiency with subacute disturbance of consciousness.
Pediatr Int. 2024 Jan-Dec;66(1):e15720. doi: 10.1111/ped.15720.
8
Pearls & oy-sters: familial epileptic encephalopathy due to methylenetetrahydrofolate reductase deficiency.珍闻与病例：亚甲基四氢叶酸还原酶缺乏所致的家族性癫痫性脑病
Neurology. 2014 Jul 15;83(3):e41-4. doi: 10.1212/WNL.0000000000000591.
9
Comparison of Cystathionine Beta-Synthase (CBS) and Methylene Tetrahydrofolate Reductase (MTHFR) Deficiency in Children with Homocystinuria.
Indian J Pediatr. 2024 Nov;91(11):1198. doi: 10.1007/s12098-024-05254-3. Epub 2024 Sep 3.
10
Early treatment using betaine and methionine for a neonate with MTHFR deficiency.对一名患有亚甲基四氢叶酸还原酶（MTHFR）缺乏症的新生儿早期使用甜菜碱和蛋氨酸进行治疗。
Pediatr Int. 2019 Dec;61(12):1265-1266. doi: 10.1111/ped.14018. Epub 2019 Nov 28.

引用本文的文献

1
Resveratrol improves lipid profile and recovers heart function in postoperative CABG patients.白藜芦醇可改善冠状动脉旁路移植术（CABG）术后患者的血脂水平并恢复心脏功能。
Mol Cell Biochem. 2025 Jul 17. doi: 10.1007/s11010-025-05351-7.
2
COVID-19 Causes Ferroptosis and Oxidative Stress in Human Endothelial Cells.新型冠状病毒肺炎导致人内皮细胞发生铁死亡和氧化应激。
Antioxidants (Basel). 2023 Jan 31;12(2):326. doi: 10.3390/antiox12020326.
3
The Effect of Resveratrol on Blood Lipid Profile: A Dose-Response Meta-Analysis of Randomized Controlled Trials.白藜芦醇对血脂谱的影响：随机对照试验的剂量反应荟萃分析。
Nutrients. 2022 Sep 11;14(18):3755. doi: 10.3390/nu14183755.

本文引用的文献

1
SIRT1 pharmacological activation rescues vascular dysfunction and prevents thrombosis in MTHFR deficiency.SIRT1 药理学激活可挽救 MTHFR 缺乏症中的血管功能障碍并预防血栓形成。
Cell Mol Life Sci. 2022 Jul 11;79(8):410. doi: 10.1007/s00018-022-04429-5.
2
Methylenetetrahydrofolate (MTHFR), the One-Carbon Cycle, and Cardiovascular Risks.亚甲基四氢叶酸还原酶（MTHFR）、一碳循环与心血管风险
Nutrients. 2021 Dec 20;13(12):4562. doi: 10.3390/nu13124562.
3
Association between MTHFR C677T/A1298C and susceptibility to autism spectrum disorders: a meta-analysis.亚甲基四氢叶酸还原酶（MTHFR）C677T/A1298C与自闭症谱系障碍易感性之间的关联：一项荟萃分析。
BMC Pediatr. 2020 Sep 24;20(1):449. doi: 10.1186/s12887-020-02330-3.
4
Impact of methylenetetrahydrofolate reductase C677T polymorphism on the efficacy of photodynamic therapy in patients with neovascular age-related macular degeneration.亚甲基四氢叶酸还原酶 C677T 多态性对光动力疗法治疗年龄相关性黄斑变性新生血管的疗效影响。
Sci Rep. 2019 Feb 22;9(1):2614. doi: 10.1038/s41598-019-38919-7.
5
Methylenetetrahydrofolate reductase and psychiatric diseases.亚甲基四氢叶酸还原酶与精神疾病。
Transl Psychiatry. 2018 Nov 5;8(1):242. doi: 10.1038/s41398-018-0276-6.
6
Resveratrol and Cardiovascular Diseases.白藜芦醇与心血管疾病
Nutrients. 2016 May 2;8(5):250. doi: 10.3390/nu8050250.
7
A selective microRNA-based strategy inhibits restenosis while preserving endothelial function.一种基于微小RNA的选择性策略可抑制再狭窄，同时保留内皮功能。
J Clin Invest. 2014 Sep;124(9):4102-14. doi: 10.1172/JCI76069. Epub 2014 Aug 18.
8
Pearls & oy-sters: familial epileptic encephalopathy due to methylenetetrahydrofolate reductase deficiency.珍闻与病例：亚甲基四氢叶酸还原酶缺乏所致的家族性癫痫性脑病
Neurology. 2014 Jul 15;83(3):e41-4. doi: 10.1212/WNL.0000000000000591.
9
Prospective study of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of all-cause and cardiovascular disease mortality among 6000 US adults.前瞻性研究亚甲基四氢叶酸还原酶（MTHFR）C677T 变异与 6000 名美国成年人全因和心血管疾病死亡率的关系。
Am J Clin Nutr. 2012 May;95(5):1245-53. doi: 10.3945/ajcn.111.022384. Epub 2012 Apr 4.
10
Sirtuins and disease: the road ahead.沉默调节蛋白与疾病：未来之路。
Front Pharmacol. 2012 Jan 31;3:4. doi: 10.3389/fphar.2012.00004. eCollection 2012.