Goy J J, Stumpe F, Kappenberger L, Sadeghi H
Schweiz Med Wochenschr. 1987 May 23;117(21):801-3.
Although thrombosis of St. Jude valve prosthesis is rare, we report a case of multiple thromboembolism in a patient who had stopped anticoagulant therapy. The consequences were very severe since two abdominal operations (colonic resection) were necessary. Since the patient was not compliant with anticoagulant therapy, aortic valve replacement was performed and a biologic valve implanted. The postoperative phase was long but the patient left the hospital after two months' treatment. This case again demonstrates the importance of anticoagulant therapy in patients with a prosthetic heart valve. Addition of dipyridamole diminished the risk of thromboembolic accident and should be added to the anticoagulant regimen.
尽管圣犹达瓣膜假体血栓形成罕见，但我们报告一例停用抗凝治疗患者发生多次血栓栓塞的病例。后果非常严重，因为需要进行两次腹部手术（结肠切除术）。由于患者不依从抗凝治疗，遂行主动脉瓣置换并植入生物瓣膜。术后恢复阶段漫长，但患者经过两个月治疗后出院。该病例再次证明抗凝治疗在人工心脏瓣膜患者中的重要性。加用双嘧达莫可降低血栓栓塞事件风险，应添加到抗凝方案中。
