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Saturation of ara-CTP accumulation during high-dose ara-C therapy: pharmacologic rationale for intermediate-dose ara-C.

作者信息

Plunkett W, Liliemark J O, Estey E, Keating M J

出版信息

Semin Oncol. 1987 Jun;14(2 Suppl 1):159-66.

PMID:3589690
Abstract
摘要

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1
Saturation of ara-CTP accumulation during high-dose ara-C therapy: pharmacologic rationale for intermediate-dose ara-C.大剂量阿糖胞苷治疗期间阿糖胞苷三磷酸（ara-CTP）蓄积的饱和现象：中等剂量阿糖胞苷的药理学依据。
Semin Oncol. 1987 Jun;14(2 Suppl 1):159-66.
2
Saturation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate accumulation in leukemia cells during high-dose 1-beta-D-arabinofuranosylcytosine therapy.高剂量1-β-D-阿拉伯呋喃糖基胞嘧啶治疗期间白血病细胞中1-β-D-阿拉伯呋喃糖基胞嘧啶5'-三磷酸积累的饱和度
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Effect of m-AMSA on the cellular pharmacology of ara-CTP in human leukemic cells during therapy with high-dose ara-C.在大剂量阿糖胞苷治疗期间，甲氧基柔红霉素对阿糖胞苷三磷酸在人白血病细胞中的细胞药理学作用。
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ara-C in plasma and ara-CTP in leukemic cells after subcutaneous injection and continuous intravenous infusion of ara-C in patients with acute nonlymphoblastic leukemia.
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Minimum dose of fludarabine for the maximal modulation of 1-beta-D-arabinofuranosylcytosine triphosphate in human leukemia blasts during therapy.治疗期间，氟达拉滨的最小剂量对人白血病原始细胞中1-β-D-阿拉伯呋喃糖基胞嘧啶三磷酸的最大调节作用。
Clin Cancer Res. 1997 Sep;3(9):1539-45.
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Effect of amsacrine on ara-CTP cellular pharmacology in human leukemia cells during high-dose cytarabine therapy.大剂量阿糖胞苷治疗期间安吖啶对人白血病细胞中ara-CTP细胞药理学的影响。
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Relationship between plasma Ara-C and intracellular Ara-CTP pools under conditions of continuous infusion and high-dose Ara-C treatment.
Med Pediatr Oncol. 1982;10 Suppl 1:33-43. doi: 10.1002/mpo.2950100706.
8
Role of dephosphorylation in accumulation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in human lymphoblastic cell lines with reference to their drug sensitivity.去磷酸化在人淋巴细胞系中1-β-D-阿拉伯呋喃糖基胞嘧啶5'-三磷酸积累中的作用及其与药物敏感性的关系
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Modulation of arabinosylnucleoside metabolism by arabinosylnucleotides in human leukemia cells.阿拉伯糖基核苷酸对人白血病细胞中阿拉伯糖基核苷代谢的调节作用。
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Ara-CTP metabolism following hydroxyurea or methotrexate treatment in human leukemia cell lines.羟基脲或甲氨蝶呤治疗人白血病细胞系后的阿糖胞苷三磷酸（Ara-CTP）代谢
Adv Exp Med Biol. 1989;253B:363-7. doi: 10.1007/978-1-4684-5676-9_53.

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