• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

意大利再生医学用生物材料：主要研究中心的简要现状概述。

Biomaterials for Regenerative Medicine in Italy: Brief State of the Art of the Principal Research Centers.

机构信息

Translational Medicine Department, University of Ferrara, 44121 Ferrara, Italy.

Medical Sciences Department, University of Ferrara, 44121 Ferrara, Italy.

出版信息

Int J Mol Sci. 2022 Jul 26;23(15):8245. doi: 10.3390/ijms23158245.

DOI:10.3390/ijms23158245
PMID:35897825
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9368060/
Abstract

Regenerative medicine is the branch of medicine that effectively uses stem cell therapy and tissue engineering strategies to guide the healing or replacement of damaged tissues or organs. A crucial element is undoubtedly the biomaterial that guides biological events to restore tissue continuity. The polymers, natural or synthetic, find wide application thanks to their great adaptability. In fact, they can be used as principal components, coatings or vehicles to functionalize several biomaterials. There are many leading centers for the research and development of biomaterials in Italy. The aim of this review is to provide an overview of the current state of the art on polymer research for regenerative medicine purposes. The last five years of scientific production of the main Italian research centers has been screened to analyze the current advancement in tissue engineering in order to highlight inputs for the development of novel biomaterials and strategies.

摘要

再生医学是医学的一个分支，它有效地利用干细胞治疗和组织工程策略来指导受损组织或器官的愈合或替代。一个关键要素无疑是指导生物事件以恢复组织连续性的生物材料。聚合物，无论是天然的还是合成的，由于其高度的适应性而得到广泛应用。事实上，它们可以用作主要成分、涂层或载体，以使多种生物材料功能化。意大利有许多从事生物材料研发的领先中心。本文旨在综述用于再生医学目的的聚合物研究的最新进展。对主要意大利研究中心过去五年的科学产出进行了筛选，以分析组织工程的当前进展，从而突出新型生物材料和策略的发展方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5801/9368060/0a88767a9796/ijms-23-08245-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5801/9368060/e326ec116a05/ijms-23-08245-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5801/9368060/ec848e19c9c7/ijms-23-08245-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5801/9368060/d7c981402f8b/ijms-23-08245-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5801/9368060/f5124eb55224/ijms-23-08245-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5801/9368060/8bdaba3d8efe/ijms-23-08245-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5801/9368060/4026bb2ad725/ijms-23-08245-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5801/9368060/0a88767a9796/ijms-23-08245-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5801/9368060/e326ec116a05/ijms-23-08245-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5801/9368060/ec848e19c9c7/ijms-23-08245-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5801/9368060/d7c981402f8b/ijms-23-08245-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5801/9368060/f5124eb55224/ijms-23-08245-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5801/9368060/8bdaba3d8efe/ijms-23-08245-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5801/9368060/4026bb2ad725/ijms-23-08245-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5801/9368060/0a88767a9796/ijms-23-08245-g007.jpg

相似文献

1
Biomaterials for Regenerative Medicine in Italy: Brief State of the Art of the Principal Research Centers.意大利再生医学用生物材料：主要研究中心的简要现状概述。
Int J Mol Sci. 2022 Jul 26;23(15):8245. doi: 10.3390/ijms23158245.
2
An overview of the therapeutic potential of regenerative medicine in cutaneous wound healing.再生医学在皮肤伤口愈合中的治疗潜力概述。
Int Wound J. 2017 Jun;14(3):450-459. doi: 10.1111/iwj.12735. Epub 2017 Mar 6.
3
Biomaterials for Regenerative Medicine: Historical Perspectives and Current Trends.再生医学用生物材料：历史视角与当前趋势。
Adv Exp Med Biol. 2018;1119:1-19. doi: 10.1007/5584_2018_278.
4
Biomaterials and Regenerative Medicine in Urology.泌尿外科中的生物材料和再生医学。
Adv Exp Med Biol. 2018;1107:189-198. doi: 10.1007/5584_2017_139.
5
Biomaterial-Assisted Regenerative Medicine.生物材料辅助再生医学。
Int J Mol Sci. 2021 Aug 12;22(16):8657. doi: 10.3390/ijms22168657.
6
Bio Mimicking of Extracellular Matrix.细胞外基质仿生。
Adv Exp Med Biol. 2019;1174:371-399. doi: 10.1007/978-981-13-9791-2_12.
7
Engineering and Functionalization of Gelatin Biomaterials: From Cell Culture to Medical Applications.明胶生物材料的工程化和功能化：从细胞培养到医学应用。
Tissue Eng Part B Rev. 2020 Apr;26(2):164-180. doi: 10.1089/ten.TEB.2019.0256. Epub 2020 Feb 4.
8
Biomaterials in Relation to Dentistry.与牙科相关的生物材料
Front Oral Biol. 2015;17:1-12. doi: 10.1159/000381686. Epub 2015 Jul 20.
9
Advances in Biodegradable Polymers and Biomaterials for Medical Applications-A Review.可生物降解聚合物和生物材料在医学应用中的进展综述
Molecules. 2023 Aug 24;28(17):6213. doi: 10.3390/molecules28176213.
10
Gelatin as Biomaterial for Tissue Engineering.明胶作为组织工程的生物材料。
Curr Pharm Des. 2017;23(24):3567-3584. doi: 10.2174/0929867324666170511123101.

引用本文的文献

1
Bone Defect Treatment in Regenerative Medicine: Exploring Natural and Synthetic Bone Substitutes.再生医学中的骨缺损治疗：探索天然和合成骨替代物
Int J Mol Sci. 2025 Mar 27;26(7):3085. doi: 10.3390/ijms26073085.
2
Apple Derived Exosomes Improve Collagen Type I Production and Decrease MMPs during Aging of the Skin through Downregulation of the NF-κB Pathway as Mode of Action.苹果来源的外泌体通过下调 NF-κB 通路作为作用模式改善皮肤老化过程中的 I 型胶原蛋白产生并减少 MMPs。
Cells. 2022 Dec 7;11(24):3950. doi: 10.3390/cells11243950.

本文引用的文献

1
Preclinical Development of Bioengineered Allografts Derived from Decellularized Human Diaphragm.源自脱细胞人膈肌的生物工程同种异体移植物的临床前开发
Biomedicines. 2022 Mar 22;10(4):739. doi: 10.3390/biomedicines10040739.
2
Silk-Based Matrices and c-Kit-Positive Cardiac Progenitor Cells for a Cellularized Silk Fibroin Scaffold: Study of an in vivo Model.基于丝素的基质和 c-Kit 阳性心脏祖细胞用于细胞化丝素纤维蛋白支架：体内模型研究。
Cells Tissues Organs. 2023;212(3):258-271. doi: 10.1159/000522568. Epub 2022 Feb 14.
3
Characterization of Physical, Mechanical, and Biological Properties of SilkBridge Nerve Conduit after Enzymatic Hydrolysis.
酶解后SilkBridge神经导管的物理、力学和生物学特性表征
ACS Appl Bio Mater. 2020 Dec 21;3(12):8361-8374. doi: 10.1021/acsabm.0c00613. Epub 2020 Nov 10.
4
Genipin-Based Crosslinking of Jellyfish Collagen 3D Hydrogels.基于京尼平的海蜇胶原蛋白3D水凝胶交联
Gels. 2021 Nov 27;7(4):238. doi: 10.3390/gels7040238.
5
3D Printing in Alginic Acid Bath of In-Situ Crosslinked Collagen Composite Scaffolds.原位交联胶原复合支架在海藻酸浴中的3D打印
Materials (Basel). 2021 Nov 8;14(21):6720. doi: 10.3390/ma14216720.
6
Multifunctional 3D-Printed Magnetic Polycaprolactone/Hydroxyapatite Scaffolds for Bone Tissue Engineering.用于骨组织工程的多功能3D打印磁性聚己内酯/羟基磷灰石支架
Polymers (Basel). 2021 Nov 5;13(21):3825. doi: 10.3390/polym13213825.
7
Dual-Functional Nano-Functionalized Titanium Scaffolds to Inhibit Bacterial Growth and Enhance Osteointegration.用于抑制细菌生长和增强骨整合的双功能纳米功能化钛支架
Nanomaterials (Basel). 2021 Oct 7;11(10):2634. doi: 10.3390/nano11102634.
8
Soft Hydrogel Inspired by Elastomeric Proteins.受弹性蛋白启发的软水凝胶。
ACS Biomater Sci Eng. 2021 Nov 8;7(11):5028-5038. doi: 10.1021/acsbiomaterials.1c00817. Epub 2021 Oct 22.
9
Bone Regeneration in Load-Bearing Segmental Defects, Guided by Biomorphic, Hierarchically Structured Apatitic Scaffold.生物形态、层次结构的磷灰石支架引导下承重节段性骨缺损的骨再生
Front Bioeng Biotechnol. 2021 Sep 27;9:734486. doi: 10.3389/fbioe.2021.734486. eCollection 2021.
10
Thermosensitive chitosan-based hydrogels supporting motor neuron-like NSC-34 cell differentiation.热敏性壳聚糖基水凝胶支持运动神经元样 NSC-34 细胞分化。
Biomater Sci. 2021 Nov 9;9(22):7492-7503. doi: 10.1039/d1bm01129d.