• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

游走癌细胞:无原发性肿瘤证据的转移性肾细胞癌

Wandering Cancer Cells: Metastatic Renal Cell Carcinoma Without Evidence of a Primary Tumor.

作者信息

Hlaing Swe Swe, Desai Devashish, Goyal Aakash, Rai Navjot, Swaab Ronald

机构信息

Internal Medicine, Crozer-Chester Medical Center, Upland, USA.

Hematology and Medical Oncology, Crozer-Chester Medical Center, Upland, USA.

出版信息

Cureus. 2022 Jun 24;14(6):e26305. doi: 10.7759/cureus.26305. eCollection 2022 Jun.

DOI:10.7759/cureus.26305
PMID:35898368
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9309091/
Abstract

Renal cell carcinoma (RCC) usually presents clinically in the advanced stage including bone metastasis. However metastatic RCC without evidence of a primary tumor in the kidney is extremely rare. We herein report a case of a 70-year-old male initially evaluated for bone lesion and diagnosed with biopsy-proven metastatic clear cell RCC without a renal primary. Given the rare nature of the disease, there is no standardized course of treatment that has yet been established. We believe that our case will add to the body of knowledge about uncommon oncologic instances and consolidate the information that has already been published.

摘要

肾细胞癌(RCC)通常在晚期临床出现,包括骨转移。然而,没有肾脏原发性肿瘤证据的转移性RCC极为罕见。我们在此报告一例70岁男性病例,该患者最初因骨病变接受评估,经活检证实为无肾原发性的转移性透明细胞RCC。鉴于该疾病的罕见性,尚未建立标准化的治疗方案。我们相信,我们的病例将增加有关罕见肿瘤病例的知识体系,并巩固已发表的信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/301f/9309091/b2a2953f3afc/cureus-0014-00000026305-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/301f/9309091/d09736f49f71/cureus-0014-00000026305-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/301f/9309091/ed6184a1a467/cureus-0014-00000026305-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/301f/9309091/5872f8c56d75/cureus-0014-00000026305-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/301f/9309091/b2a2953f3afc/cureus-0014-00000026305-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/301f/9309091/d09736f49f71/cureus-0014-00000026305-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/301f/9309091/ed6184a1a467/cureus-0014-00000026305-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/301f/9309091/5872f8c56d75/cureus-0014-00000026305-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/301f/9309091/b2a2953f3afc/cureus-0014-00000026305-i04.jpg

相似文献

1
Wandering Cancer Cells: Metastatic Renal Cell Carcinoma Without Evidence of a Primary Tumor.游走癌细胞:无原发性肿瘤证据的转移性肾细胞癌
Cureus. 2022 Jun 24;14(6):e26305. doi: 10.7759/cureus.26305. eCollection 2022 Jun.
2
Tumor-to-tumor metastases: papillary thyroid carcinoma into a clear cell renal cell carcinoma.肿瘤至肿瘤转移:甲状腺乳头状癌转移至肾透明细胞癌
J Otolaryngol Head Neck Surg. 2017 Mar 1;46(1):17. doi: 10.1186/s40463-017-0193-3.
3
Skin Metastasis of Renal Cell Carcinoma: A Case Report.肾细胞癌皮肤转移:一例报告
Cureus. 2018 Nov 19;10(11):e3614. doi: 10.7759/cureus.3614.
4
Clinically Silent, Metastatic Renal Cell Carcinoma Detected on Routine Screening Mammogram: A Report of a Rare Case and Review of Literature.常规筛查乳房X光检查发现的临床隐匿性转移性肾细胞癌:1例罕见病例报告及文献复习
Cureus. 2023 Nov 6;15(11):e48352. doi: 10.7759/cureus.48352. eCollection 2023 Nov.
5
Tumor-to-Tumor Metastasis - a Unique Case of Clear Cell Renal Cell Carcinoma Harboring Metastasis of Adenocarcinoma of Unknown Origin.肿瘤-to-肿瘤转移——一例独特的透明细胞肾细胞癌伴有不明原发腺癌转移的病例
Klin Onkol. 2018 Fall;31(5):366-370. doi: 10.14735/amko2018366.
6
Metastatic Renal cell Carcinoma Presenting as a clear-cell Tumor in Tongue: A Case Report.转移性肾细胞癌表现为舌部透明细胞肿瘤:一例报告
Iran J Otorhinolaryngol. 2014 Jul;26(76):185-90.
7
Metastatic renal cell carcinoma in a supraclavicular lymph node with no known primary: a case report.锁骨上淋巴结转移性肾细胞癌伴无已知原发灶:病例报告。
Cancer Res Treat. 2012 Sep;44(3):215-8. doi: 10.4143/crt.2012.44.3.215. Epub 2012 Sep 30.
8
Metastatic clear cell renal cell carcinoma to the forearm without identifiable primary renal mass.转移性透明细胞肾细胞癌累及前臂,未发现原发性肾肿块。
Urol Case Rep. 2019 Aug 6;27:100989. doi: 10.1016/j.eucr.2019.100989. eCollection 2019 Nov.
9
Bone Marrow Metastasis in Clear Cell Renal Cell Carcinoma: A Case Study.透明细胞肾细胞癌中的骨髓转移:病例研究
Cureus. 2019 Mar 6;11(3):e4181. doi: 10.7759/cureus.4181.
10
Metastatic renal cell carcinoma without evidence of a primary renal tumour.转移性肾细胞癌,无原发性肾肿瘤证据。
Curr Oncol. 2014 Jun;21(3):e521-4. doi: 10.3747/co.21.1914.

引用本文的文献

1
Renal cell carcinoma metastasis without a primary: A case report.无原发灶的肾细胞癌转移:一例报告。
Urol Case Rep. 2024 Jan 31;53:102658. doi: 10.1016/j.eucr.2024.102658. eCollection 2024 Mar.
2
Solitary vertebral metastasis of unknown primary renal cell carcinoma treated with surgical resection plus tyrosine kinase inhibitor: A case report.手术切除联合酪氨酸激酶抑制剂治疗原发性不明的孤立性肾细胞癌椎体转移:1例报告
Int J Surg Case Rep. 2024 Jan;114:109217. doi: 10.1016/j.ijscr.2023.109217. Epub 2023 Dec 31.
3
Combined Immunotherapy and Tyrosine Kinase Inhibitor Treatment for Metastatic Renal Cell Carcinoma With Unknown Primary Origin: A Report of Two Cases and Literature Review.

本文引用的文献

1
Orbit and sinonasal metastasis as presenting sign of renal cell carcinoma.眼眶及鼻窦转移作为肾细胞癌的首发症状
BMJ Case Rep. 2021 Apr 13;14(4):e240588. doi: 10.1136/bcr-2020-240588.
2
Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma.肿瘤与免疫重编程在晚期肾细胞癌免疫治疗中的作用
Cancer Cell. 2021 May 10;39(5):649-661.e5. doi: 10.1016/j.ccell.2021.02.015. Epub 2021 Mar 11.
3
An evaluation of nivolumab for the treatment of metastatic renal cell carcinoma.纳武利尤单抗治疗转移性肾细胞癌的评价。
联合免疫治疗和酪氨酸激酶抑制剂治疗原发灶不明转移性肾细胞癌:两例报告及文献复习。
In Vivo. 2023 Jul-Aug;37(4):1905-1913. doi: 10.21873/invivo.13285.
Expert Opin Biol Ther. 2018 Jun;18(6):695-705. doi: 10.1080/14712598.2018.1478962. Epub 2018 Jun 4.
4
Skeletal metastasis in renal cell carcinoma: A review.肾细胞癌的骨转移:综述
Ann Med Surg (Lond). 2018 Jan 31;27:9-16. doi: 10.1016/j.amsu.2018.01.002. eCollection 2018 Mar.
5
The International Metastatic Renal Cell Carcinoma Database Consortium model as a prognostic tool in patients with metastatic renal cell carcinoma previously treated with first-line targeted therapy: a population-based study.国际转移性肾细胞癌数据库联盟模型作为一线靶向治疗后转移性肾细胞癌患者的预后工具:一项基于人群的研究。
Lancet Oncol. 2015 Mar;16(3):293-300. doi: 10.1016/S1470-2045(14)71222-7. Epub 2015 Feb 12.
6
Metastatic renal cell carcinoma without evidence of a primary renal tumour.转移性肾细胞癌,无原发性肾肿瘤证据。
Curr Oncol. 2014 Jun;21(3):e521-4. doi: 10.3747/co.21.1914.
7
The evolving landscape of metastatic renal cell carcinoma.转移性肾细胞癌的不断演变态势
Am Soc Clin Oncol Educ Book. 2012:299-302. doi: 10.14694/EdBook_AM.2012.32.25.
8
Renal cell carcinoma presenting as mandibular metastasis.以下颌骨转移为表现的肾细胞癌。
Saudi J Kidney Dis Transpl. 2013 Jul;24(4):789-92. doi: 10.4103/1319-2442.113889.
9
Distribution of metastatic sites in renal cell carcinoma: a population-based analysis.肾细胞癌转移部位的分布:一项基于人群的分析。
Ann Oncol. 2012 Apr;23(4):973-80. doi: 10.1093/annonc/mdr362. Epub 2011 Sep 2.
10
Renal cell cancer without a renal primary.无肾脏原发灶的肾细胞癌。
World J Surg Oncol. 2010 Mar 22;8:18. doi: 10.1186/1477-7819-8-18.