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本研究旨在通过观察苏醒质量、血流动力学和不良反应来评估瑞芬太尼复合丙泊酚在肿瘤开颅术中的效果。

The Efficacy of Remifentanil Combined with Propofol in Craniotomy for Tumor Was Evaluated by Wake Quality, Hemodynamics, and Adverse Reactions.

机构信息

Department of Anesthesiology, Tianjin Huanhu Hospital, Tianjin 300350, China.

Department of Operation Room, Tianjin Huanhu Hospital, Tianjin 300350, China.

出版信息

Biomed Res Int. 2022 Jul 18;2022:4861043. doi: 10.1155/2022/4861043. eCollection 2022.

Abstract

In order to investigate the effect of remifentanil combined with propofol on awakening of craniotomy for tumor, a retrospective analysis is conducted. 86 patients who underwent craniotomy for brain tumor in our hospital from July 2020 to December 2021 are chosen to observe the quality of awakening, hemodynamic parameters, and the occurrence of adverse reactions. All patients are divided into group A ( = 43) and group B ( = 43) according to the use of anesthesia drugs. The intraoperative awakening quality and the hemodynamic parameters during different periods of the two groups are compared. The experimental results show that the incidence of postoperative adverse reactions in group B is significantly lower than that in group A ( < 0.05). It is clearly evident that remifentanil combined with protocol has good intraoperative wake-up effect in craniotomy for tumor and maintain the hemodynamic stability of patients. Also, it can obtain high wake-up quality and effectively reduce postoperative adverse reactions.

摘要

为了研究瑞芬太尼联合丙泊酚对肿瘤开颅术苏醒的影响,进行了回顾性分析。选择我院 2020 年 7 月至 2021 年 12 月期间 86 例行脑肿瘤开颅术的患者进行观察,以观察苏醒质量、血流动力学参数和不良反应的发生情况。所有患者根据麻醉药物的使用分为 A 组(n=43)和 B 组(n=43)。比较两组患者不同时期的术中苏醒质量和血流动力学参数。实验结果表明,B 组术后不良反应发生率明显低于 A 组(<0.05)。显然,瑞芬太尼联合方案在肿瘤开颅术中具有良好的术中唤醒效果,维持患者的血流动力学稳定。此外,它还可以获得较高的唤醒质量,有效降低术后不良反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1235/9314166/bf08b6c63929/BMRI2022-4861043.001.jpg

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