Suzuki Yuka, Hoshi Koki, Tominaga Keiichi, Inaba Yasunori, Yoshinaga Tomonori, Kojimahara Shunsuke, Maki Ryuichi, Nemoto Rena, Tetsuka Yugo, Kawata Yosuke, Yamamiya Akira, Sugaya Takeshi, Iso Yukihiro, Takada-Owada Atsuko, Ishida Kazuyuki, Goda Kenichi, Irisawa Atsushi
Department of Gastroenterology Dokkyo Medical University School of Medicine Tochigi Japan.
Department of Hepato-Biliary-Pancreatic Surgery Dokkyo Medical University School of Medicine Tochigi Japan.
DEN Open. 2022 Jun 20;3(1):e144. doi: 10.1002/deo2.144. eCollection 2023 Apr.
A 38-year-old woman was admitted to our hospital for a detailed examination of jaundice. Three years before, she had undergone a right total mastectomy and axillary lymph node dissection of her right breast because of cancer. Histopathological evaluation revealed invasive ductal carcinoma. Postoperatively, because multiple bone metastases were found, she underwent chemoradiotherapy. Endoscopic retrograde cholangiopancreatography was performed, which revealed widespread multiple stenoses with a smooth surface from the intrahepatic to the extrahepatic bile duct. A transpapillary biliary biopsy was performed. Histopathological examination revealed adenocarcinoma extending into the subepithelium of the bile duct. The obtained cancer cells were similar to those of the earlier invasive breast cancer. This rare case demonstrates bile duct metastasis of breast cancer with specific endoscopic retrograde cholangiopancreatography findings.
一名38岁女性因黄疸进行详细检查而入住我院。三年前，她因癌症接受了右乳全切除术及右腋窝淋巴结清扫术。组织病理学评估显示为浸润性导管癌。术后，因发现多处骨转移，她接受了放化疗。进行了内镜逆行胰胆管造影，结果显示从肝内胆管到肝外胆管广泛存在多个表面光滑的狭窄。进行了经乳头胆管活检。组织病理学检查显示腺癌侵犯至胆管上皮下。所获得的癌细胞与早期浸润性乳腺癌的癌细胞相似。这一罕见病例展示了具有特定内镜逆行胰胆管造影表现的乳腺癌胆管转移。
