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基于微生物群的伊维菌素在COVID-19中作用机制的假说:伊维菌素通过滋养双歧杆菌来增强免疫力。

Microbiome-Based Hypothesis on Ivermectin's Mechanism in COVID-19: Ivermectin Feeds Bifidobacteria to Boost Immunity.

作者信息

Hazan Sabine

机构信息

Progenabiome, LLC, Ventura, CA, United States.

出版信息

Front Microbiol. 2022 Jul 11;13:952321. doi: 10.3389/fmicb.2022.952321. eCollection 2022.

DOI:10.3389/fmicb.2022.952321
PMID:35898916
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9309549/
Abstract

Ivermectin is an anti-parasitic agent that has gained attention as a potential COVID-19 therapeutic. It is a compound of the type Avermectin, which is a fermented by-product of . is a member of the same phylum as spp., suggesting it may have a symbiotic relation with . Decreased levels are observed in COVID-19 susceptibility states, including old age, autoimmune disorder, and obesity. We hypothesize that Ivermectin, as a by-product of fermentation, is capable of feeding , thereby possibly preventing against COVID-19 susceptibilities. Moreover, may be capable of boosting natural immunity, offering more direct COVID-19 protection. These data concord with our study, as well as others, that show Ivermectin protects against COVID-19.

摘要

伊维菌素是一种抗寄生虫药物,作为一种潜在的新冠治疗药物而受到关注。它是阿维菌素类型的化合物,是……的发酵副产物。……与……属于同一门,这表明它可能与……有共生关系。在包括老年、自身免疫性疾病和肥胖在内的新冠易感性状态中观察到……水平降低。我们假设,作为……发酵的副产物,伊维菌素能够为……提供养分,从而有可能预防新冠易感性。此外,……可能能够增强自然免疫力,提供更直接的新冠防护。这些数据与我们的研究以及其他研究一致,这些研究表明伊维菌素可预防新冠。

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Lost microbes of COVID-19: , depletion and decreased microbiome diversity associated with SARS-CoV-2 infection severity.新冠病毒丢失的微生物:与 SARS-CoV-2 感染严重程度相关的、耗尽和减少的微生物组多样性。
BMJ Open Gastroenterol. 2022 Apr;9(1). doi: 10.1136/bmjgast-2022-000871.
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Effect of Early Treatment with Ivermectin among Patients with Covid-19.COVID-19 患者早期使用伊维菌素治疗的效果。
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Infect Dis Rep. 2022 Mar 3;14(2):160-168. doi: 10.3390/idr14020020.
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