Huang Shibin, Li Qi
Department of Otolaryngology, The Second Affiliated Hospital of Jiaxing University, No. 1518, Huancheng North Road, Jiaxing, Zhejiang 314000, China.
Department of Anesthesiology, The Second Affiliated Hospital of Jiaxing Universit, No. 1518, Huancheng North Road, Jiaxing, Zhejiang 314000, China.
Evid Based Complement Alternat Med. 2022 Jul 18;2022:6192409. doi: 10.1155/2022/6192409. eCollection 2022.
The aim is to investigate and compare the anesthesia effect of cisatracurium besylate and mivacurium chloride otolaryngology surgery.
108 patients who underwent ENT surgery under general anesthesia in our hospital from November 2021 to March 2022 were recruited for retrospective analysis, in which patients in the experimental group A were anesthetized with cisatracurium besylate and patients in the experimental group B were anesthetized with mivacurium, and the anesthetic effects and recovery of the two groups were compared and analyzed.
There was no significant difference in mean arterial pressure, heart rate, and pulse oximetry levels between the two groups at the six time points of admission, anesthesia induction, intubation, end of operation, recovery of consciousness, and extubation (all > 0.05). The train of four stimulation values at end of operation, recovery of consciousness, and extubation were significantly higher than those of the experimental group A (all > 0.05). The recovery time of self-consciousness, extubation time, and eye-opening time of the experimental group B were significantly shorter than those of the experimental group A, and the occurrence of agitation was significantly less than that of the experimental group A (all > 0.05). The total incidence of adverse conditions in the experimental group B was significantly lower than that in the experimental group A ( > 0.05).
Compared with cisatracurium besylate in otolaryngology surgery, mivacurium chloride anesthesia offers a promising route with respect to less impact on hemodynamics, faster postoperative recovery, absence of the accumulation of neuromuscular blockade, less adverse reactions, and higher safety.
探讨并比较苯磺顺阿曲库铵和米库氯铵在耳鼻喉科手术中的麻醉效果。
选取2021年11月至2022年3月在我院接受全身麻醉下耳鼻喉科手术的108例患者进行回顾性分析，其中A实验组患者采用苯磺顺阿曲库铵麻醉，B实验组患者采用米库氯铵麻醉，比较分析两组的麻醉效果及恢复情况。
两组患者在入院、麻醉诱导、插管、手术结束、意识恢复、拔管六个时间点的平均动脉压、心率、脉搏血氧饱和度水平比较，差异均无统计学意义（均P>0.05）。手术结束、意识恢复、拔管时的四个成串刺激值均显著高于A实验组（均P>0.05）。B实验组的意识恢复时间、拔管时间、睁眼时间均显著短于A实验组，躁动发生率显著低于A实验组（均P>0.05）。B实验组不良情况总发生率显著低于A实验组（P>0.05）。
在耳鼻喉科手术中，与苯磺顺阿曲库铵相比，米库氯铵麻醉对血流动力学影响较小，术后恢复较快，无神经肌肉阻滞蓄积，不良反应较少，安全性较高，具有良好的应用前景。
