[Comparative analysis of population distribution, severity, emotional, and cognitive characteristics among different side idiopathic tinnitus patients].

To provide basis for prevention and treatment by analyzing the clinical features, emotional and cognitive states and their correlations of idiopathic tinnitus. Cross-sectional study was used. Thirty-six right, 44 left, and 46 bilateral idiopathic tinnitus patients diagnosed in Beijing Tongren Hospital were prospectively enrolled from October, 2020 to February, 2022. The clinical data was recorded and the THI, DBI, STAI, and MoCA were evaluated. The clinical features and the incidence of severe tinnitus, hearing lose, anxiety, and cognitive impairment were compared by one-way ANOVA, Kruskal-Wallis , and chi-square test. The correlation between tinnitus or hearing and emotional and cognitive states were evaluated by multivariable correlation analysis. There was no significant difference in age, BMI, years of education, tinnitus duration, and the incidence of hearing loss among groups (=0.730,=0.484;=1.535,=0.219;=1.506,=0.226;χ²=4.242,=0.120;χ²=6.672,=0.083). In right, left, and bilateral tinnitus patients, the number of severe tinnitus was 12, 7, and 20 cases and the incidence was 33.3%, 15.9%, and 43.5%; the number of depression was 13, 14, and 26 cases and incidence was 36.1%, 31.8%, and 53.5%; the number of trait anxiety was 3, 2, and 10 cases and the incidence was 8.3%, 4.5%, and 21.7%. Compared with left tinnitus patients, the incidence of severe tinnitus, depression, and trait anxiety was higher in bilateral tinnitus patients (χ²=8.139,=0.004;χ²=5.558,=0.018;χ²=5.753,=0.007). The incidence of state anxiety and cognitive impairment were no significant difference among groups (χ²=0.142,=0.931;χ²=1.338,=0.512). The overall incidence of state anxiety and cognitive impairment were 16.7%(21/126) and 37.3%(47/126) respectively. There was positive correlation between THI score and BDI, S-AI, and T-AI scores (=0.529,=0.001; =0.649,<0.001; =0.483,=0.003) and negative correlation between THI and MoCA scores (=-0.364,=0.029) in right tinnitus group. The positive correlation was found between THI score and BDI, S-AI, and T-AI scores in left tinnitus group (=0.508,<0.001; =0.506,<0.001; =0.357,=0.017). The positive correlation between THI score and BDI, S-AI, and T-AI scores (=0.753,<0.001; =0.527,<0.001; =0.536,<0.001) and the positive correlation between tinnitus duration and MoCA score(=0.334,=0.023) were also found in bilateral tinnitus group.