Department of Physiotherapy, University of Pretoria, Pretoria, Enugu, Nigeria.
Department of Basic Medical Sciences, Durban University of Technology, Durban, KwaZulu-Natal, Nigeria.
Niger Postgrad Med J. 2022 Jul-Sep;29(3):262-267. doi: 10.4103/npmj.npmj_31_22.
The study aimed to derive socio-demographic-corrected norms for selecting neuropsychological (NP) battery tests for people living with HIV (PLWHIV) in Nigeria. This cross-sectional study was conducted amongst patients who attended the general outpatient clinic and junior staff of the University of Nigeria Teaching Hospital (UNTH), Ituku-Ozalla.
To determine the normative scores for select neuropsychological battery test for the detection of neurocognitive disorder amongst Nigerians PLWHIV. A sample of 92 individuals received voluntary HIV testing.
Eligibility criteria were being HIV negative, aged 18-64 years and formal education. We undertook a brief neuromedical examination to identify putative exclusion criteria. We sampled four NP tests covering seven cognitive domains and the motor speed component of the International HIV Dementia Scale (IHDS-MS). We presented the normative scores using statistics of mean, median, standard deviation (SD), kurtosis and skewness.
All the participants were Nigerians aged 18-64 years. Most (74.1%) of the participants were females. The mean and median ages of the participants were 42.6 ± 11.42 years and 44 years, respectively. The effect of gender on NP performance was limited to the digit span test (DST)-forwards, while education affected all expect IHDS-MS and DST-backwards. The cut-off scores for defining mild and severe impairment varied (moving from 1SD to 2SD) for all cognitive domains except for IHDS-MS and DST.
With these preliminary normative scores, it will be easier to identify and classify the severity of neurocognitive impairment amongst PLWHIV in Nigeria, thus facilitating the goal of keeping HIV-associated dementia to a minimum. The lack of variability in the IHDS-MS and DST is unfavourable.
本研究旨在为尼日利亚艾滋病毒感染者（PLWHIV）制定社会人口统计学校正的神经心理学（NP）测试选择规范。这是一项横断面研究，在尼日利亚恩苏卡-奥扎拉的尼日利亚大学教学医院（UNTH）普通门诊和初级医务人员中进行。
确定用于检测尼日利亚 PLWHIV 神经认知障碍的选择神经心理测试的规范分数。有 92 名个体接受了自愿的 HIV 检测。
入选标准为 HIV 阴性、年龄在 18-64 岁之间以及具有正规教育背景。我们进行了简短的神经医学检查以确定可能的排除标准。我们抽取了四项涵盖七个认知领域和国际艾滋病毒痴呆量表（IHDS-MS）运动速度成分的 NP 测试。我们使用均值、中位数、标准差（SD）、峰度和偏度的统计数据呈现规范分数。
所有参与者均为年龄在 18-64 岁之间的尼日利亚人。大多数（74.1%）参与者为女性。参与者的平均年龄和中位数年龄分别为 42.6±11.42 岁和 44 岁。性别对 NP 表现的影响仅限于数字跨度测试（DST）向前，而教育对 IHDS-MS 和 DST 向后除外。除 IHDS-MS 和 DST 外，所有认知领域的定义轻度和重度损伤的临界值（从 1SD 到 2SD）均有所不同。
有了这些初步的规范分数，将更容易识别和分类尼日利亚 PLWHIV 的神经认知障碍严重程度，从而有助于实现将艾滋病毒相关痴呆症降到最低的目标。IHDS-MS 和 DST 缺乏变异性是不利的。
