Department of Medicine III, Ludwig Maximilians University Hospital, Munich, Germany.
Division of Geriatrics, Department of Medicine, University of California, San Francisco, San Francisco, CA, United States of America.
PLoS One. 2022 Jul 28;17(7):e0271754. doi: 10.1371/journal.pone.0271754. eCollection 2022.
To assess the usability of German hospital administrative claims data (GHACD) to determine inpatient management patterns, healthcare resource utilization, and quality-of-care in patients with multiple myeloma (PwMM).
Based on German tertiary hospital's claims data (2015-2017), PwMM aged >18 years were included if they had an International Classification of Diseases, Tenth Revision, code of C90.0 or received anti-MM therapy. Subgroup analysis was performed on stem cell transplantation (SCT) patients.
Of 230 PwMM, 59.1% were men; 56.1% were aged ≥65 years. Hypertension and infections were present in 50% and 67.0%, respectively. Seventy percent of PwMM received combination therapy. Innovative drugs such as bortezomib and lenalidomide were given to 36.1% and 10.9% of the patients, respectively. Mean number of admissions and mean hospitalization length/patient were 3.69 (standard deviation (SD) 2.71 (1-16)) and 12.52 (SD 9.55 (1-68.5)) days, respectively. In-hospital mortality was recorded in 12.2%. Seventy-two percent of SCT patients (n = 88) were aged ≤65 years, 22.7% required second transplantation, and 89.8% received platelet transfusion at a mean of 1.42(SD 0.63 (1-3)).
GHACD provided relevant information essential for healthcare studies about PwMM from routine care settings. Data fundamental for quality-of-care assessment were also captured.
评估德国医院行政索赔数据（GHACD）在确定多发性骨髓瘤（PwMM）患者住院管理模式、医疗资源利用和护理质量方面的可用性。
基于德国三级医院的索赔数据（2015-2017 年），纳入年龄>18 岁且患有国际疾病分类第十版 C90.0 或接受抗-MM 治疗的 PwMM。对干细胞移植（SCT）患者进行亚组分析。
230 例 PwMM 中，59.1%为男性；56.1%年龄≥65 岁。分别有 50%和 67.0%的患者存在高血压和感染。70%的 PwMM 接受联合治疗。分别有 36.1%和 10.9%的患者使用硼替佐米和来那度胺等创新药物。患者平均住院次数和平均住院时间/人分别为 3.69（标准差 2.71[1-16]）和 12.52（标准差 9.55[1-68.5]）天。住院死亡率为 12.2%。72%的 SCT 患者（n=88）年龄≤65 岁，22.7%需要二次移植，89.8%在平均 1.42（标准差 0.63[1-3]）天接受血小板输注。
GHACD 提供了来自常规护理环境的关于 PwMM 的医疗保健研究的相关信息，这些信息对于评估护理质量也很重要。
