Department of Psychology.
Division of Biostatistics.
Rehabil Psychol. 2022 Nov;67(4):449-460. doi: 10.1037/rep0000456. Epub 2022 Jul 28.
Purpose/Objective Research: This secondary analysis of a pilot randomized controlled trial in people with multiple sclerosis (PwMS) aimed to compare mindfulness-based training (MBT), adaptive cognitive training (aCT), and a waitlist control (WL) on the use of emotion regulation strategies during daily worries and ruminations. Further, we examined cognitive functioning as a moderator of training effects.
RESEARCH METHOD/DESIGN: Sixty-one PwMS were randomized into an MBT, aCT, or a WL control group for four weeks. Participants completed daily diaries assessing their use of emotion regulation strategies and measures of cognitive functioning at pre- and posttraining. The frequency of acceptance use, maladaptive strategies, and cognitive reappraisal, as well as the success of acceptance use, were the primary outcomes of interest. We also examined whether a cognitive composite score moderated treatment gains.
Relative to pretraining, at posttraining, participants in the MBT group used acceptance more frequently, and this change was significantly greater compared to the change in aCT and WL groups. Training did not have differential effects on the frequency of maladaptive strategy and cognitive reappraisal use or on the success of acceptance use. Cognitive functioning did not moderate observed treatment gains.
CONCLUSION/IMPLICATIONS: Our findings, based on this pilot study, suggest that after brief training in mindfulness meditation, PwMS used more acceptance strategies to regulate their emotions. Future studies with larger sample sizes, longer duration of treatment, and longitudinal follow-up are needed to better understand the efficacy of mindfulness mediation for promoting affective and cognitive health in PwMS. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
目的/目标：本研究为一项针对多发性硬化症患者（PwMS）的初步随机对照试验的二次分析，旨在比较正念训练（MBT）、适应性认知训练（aCT）和等待名单对照组（WL）在日常担忧和沉思中使用情绪调节策略的效果。此外，我们还研究了认知功能作为训练效果的调节因素。
研究方法/设计：61 名 PwMS 被随机分配到 MBT、aCT 或 WL 对照组，进行为期四周的训练。参与者在训练前后完成了每日日记评估，评估他们使用情绪调节策略的情况以及认知功能的情况。主要关注的结果包括接受使用的频率、适应不良策略、认知重评，以及接受使用的成功率。我们还研究了认知综合评分是否调节了治疗效果。
与训练前相比，MBT 组的参与者在训练后更频繁地使用接受策略，与 aCT 和 WL 组相比，这种变化显著更大。训练对适应不良策略和认知重评使用的频率或接受使用的成功率没有不同的影响。认知功能没有调节观察到的治疗效果。
结论/意义：基于这项初步研究，我们的研究结果表明，在接受短暂的正念冥想训练后，PwMS 使用更多的接受策略来调节自己的情绪。需要进行更大样本量、更长治疗时间和纵向随访的未来研究，以更好地了解正念冥想对促进 PwMS 的情感和认知健康的疗效。
