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胫骨平台骨折后早期创伤性骨关节炎的放射学证据与功能较差相关。

Radiographic Evidence of Early Posttraumatic Osteoarthritis following Tibial Plateau Fracture Is Associated with Poorer Function.

机构信息

Department of Orthopedic Surgery, NYU Langone Orthopedic Hospital, New York, New York.

Department of Orthopedic Surgery, Jamaica Hospital Medical Center, New York, New York.

出版信息

J Knee Surg. 2023 Oct;36(12):1230-1237. doi: 10.1055/s-0042-1755375. Epub 2022 Jul 28.

Abstract

To determine if radiographic evidence of posttraumatic osteoarthritis (PTOA) following tibial plateau fracture correlates with poorer clinical and functional outcomes, patients with tibial plateau fractures were followed at 3, 6, and 12 months. All patients had baseline radiographs and computed tomography scan. Radiographs obtained at each follow-up were reviewed for healing, articular incongruence, hardware positional changes, and the development of postinjury arthritic change. Cohorts were determined based on the presence (PTOA) or absence (NPTOA) of radiographic evidence of PTOA. Demographics, fracture classification, complications, additional procedures, and functional status were compared between cohorts. Sixty patients had radiographic evidence of PTOA on follow-up radiographs at a mean final follow-up of 24.2 months. The NPTOA cohort was composed of 210 patients who were matched to the PTOA cohort based on age and Charlson comorbidity index. Mean time to fracture union for the overall cohort was 4.86 months. Cohorts did not differ in Schatzker classification, time to healing, injury mechanism, or baseline Short Musculoskeletal Function Assessment (SMFA). Patients with PTOA had a greater degree of initial depression and postoperative step-off, higher incidence of initial external fixator usage, higher rates of reoperation for any reason, and higher rates of wound complications. Associated soft tissue injury and meniscal repair did not coincide with the development of PTOA. Range of motion and SMFA scores were significantly worse at all time points in patients with PTOA. Although fracture patterns are similar, patients who required an initial external fixator, had a greater degree of initial depression or residual articular incongruity, underwent more procedures, and developed an infection were found to have increased incidence of PTOA. Radiographic evidence of osteoarthritis correlated with worse functional status in patients. The goal of surgery should be restoration of articular congruity and stability to mitigate the risk of PTOA, although this alone may not prevent degenerative changes. Patients with early loss of range of motion should be aggressively treated as this may precede the development of PTOA.

摘要

为了确定胫骨平台骨折后创伤后骨关节炎(PTOA)的放射学证据是否与较差的临床和功能结果相关,对胫骨平台骨折患者进行了 3、6 和 12 个月的随访。所有患者均进行基线 X 线和 CT 扫描。在每次随访时,对愈合、关节不平整、内固定位置变化以及损伤后关节炎变化的发展进行影像学评估。根据是否存在(PTOA)或不存在(NPTOA)放射学证据的 PTOA 确定队列。对队列间的人口统计学数据、骨折分类、并发症、附加程序和功能状态进行比较。在平均随访 24.2 个月的随访 X 线片上,60 例患者出现 PTOA 的放射学证据。NPTOA 队列由 210 例患者组成,这些患者根据年龄和 Charlson 合并症指数与 PTOA 队列相匹配。整个队列的骨折愈合平均时间为 4.86 个月。队列间的 Schatzker 分类、愈合时间、损伤机制或基线短肌骨骼功能评估(SMFA)无差异。PTOA 患者的初始抑郁和术后台阶高度更高,初始外固定器使用率更高,任何原因再次手术的发生率更高,伤口并发症的发生率更高。相关的软组织损伤和半月板修复与 PTOA 的发展并不一致。在所有时间点,PTOA 患者的关节活动度和 SMFA 评分均明显更差。尽管骨折模式相似,但需要初始外固定器、初始抑郁或残余关节不平整程度更大、接受更多手术且发生感染的患者,发现 PTOA 的发生率更高。放射学证据的骨关节炎与患者功能状态较差相关。手术的目标应是恢复关节的吻合度和稳定性,以降低 PTOA 的风险,尽管这本身可能无法预防退行性变化。应积极治疗早期丧失活动范围的患者,因为这可能会先于 PTOA 的发展。

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