Department of Anatomic Pathology, AC Camargo Cancer Center, São Paulo-SP, Brazil.
Int J Surg Pathol. 2023 Aug;31(5):596-599. doi: 10.1177/10668969221113474. Epub 2022 Jul 29.
Indolent NK-cell lymphoproliferative disorder of the gastrointestinal tract is a new provisional entity listed in the structure of the forthcoming fifth edition of the World Health Organization (WHO) Classification of Hematolymphoid Tumors. It was first named as "NK-cell enteropathy" and "Lymphomatoid gastropathy" by two independent series a decade ago. Molecular or cytogenetic studies have lent support to the clonal/neoplastic nature of this entity. Herein we add two of such cases that still challenge pathologists and were previously diagnosed as aggressive lymphomas of NK/T derivation.
惰性 NK 细胞胃肠淋巴组织增生性疾病是即将发布的第五版世界卫生组织（WHO）血液淋巴肿瘤分类中新列出的一个暂定实体。十年前，两个独立的研究系列首次将其命名为“NK 细胞肠病”和“淋巴瘤样胃病”。分子或细胞遗传学研究支持该实体的克隆/肿瘤性质。在此，我们增加了两个这样的病例，它们仍然对病理学家构成挑战，之前被诊断为 NK/T 来源的侵袭性淋巴瘤。
