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[以昔康类为例,考虑临床和药理学特征,非甾体抗炎药个体化选择的可能性]

[Possibilities of individual choice of NSAIDs on the example of the oxicam class, taking into account clinical and pharmacological characteristics].

作者信息

Putilina M V, Teplova N V

机构信息

Pirogov Russian National Research Medical Univesity, Moscow, Russia.

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2022;122(7):36-41. doi: 10.17116/jnevro202212207136.

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are traditionally used to relieve pain syndromes. The class of NSAIDs includes oxicams (meloxicam, tenoxicam, lornoxicam) - drugs with pronounced analgesic and anti-inflammatory effects. Oxicams have common properties of the class, but at the same time, due to structural differences from all other NSAIDs, they differ in a number of clinical and pharmacological characteristics, knowledge of which will help to individualize the choice of the drug.

摘要

非甾体抗炎药(NSAIDs)传统上用于缓解疼痛综合征。NSAIDs类药物包括昔康类(美洛昔康、替诺昔康、氯诺昔康)——具有显著镇痛和抗炎作用的药物。昔康类药物具有该类药物的共同特性,但同时,由于其与所有其他NSAIDs在结构上存在差异,它们在一些临床和药理学特征方面有所不同,了解这些特征将有助于个体化选择药物。

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