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Tofacitinib as a possible treatment for arthritis in an APDS2 patient.

作者信息

Sun Boyuan, Zhou Shuang, Yang Huaxia, Zhou Jiaxin, Leng Xiaomei, Zhang Wen, Zeng Xiaofeng

机构信息

Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College.

Peking Union Medical College, M.D. Program.

出版信息

Rheumatology (Oxford). 2023 Mar 1;62(3):e39-e41. doi: 10.1093/rheumatology/keac436.

DOI:10.1093/rheumatology/keac436
PMID:35904543
Abstract
摘要

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Tofacitinib as a possible treatment for arthritis in an APDS2 patient.托法替布作为治疗一名活化磷脂酰肌醇-3激酶δ综合征2型（APDS2）患者关节炎的一种可能疗法。
Rheumatology (Oxford). 2023 Mar 1;62(3):e39-e41. doi: 10.1093/rheumatology/keac436.
2
Tofacitinib for treatment of rheumatoid arthritis.托法替布治疗类风湿关节炎。
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Malignancy and Janus Kinase Inhibition.恶性肿瘤与Janus激酶抑制
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Tofacitinib in Combination With Conventional Disease-Modifying Antirheumatic Drugs in Patients With Active Rheumatoid Arthritis: Patient-Reported Outcomes From a Phase III Randomized Controlled Trial.托法替布联合传统改善病情抗风湿药物治疗活动性类风湿关节炎患者：一项III期随机对照试验的患者报告结局
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Successful treatment of palmoplantar pustulosis with rheumatoid arthritis, with tofacitinib: Impact of this JAK inhibitor on T-cell differentiation.托法替布成功治疗合并类风湿关节炎的掌跖脓疱病：这种JAK抑制剂对T细胞分化的影响
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Tofacitinib prevents radiographic progression in rheumatoid arthritis.托法替布可预防类风湿关节炎的影像学进展。
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Systematic literature reviews to identify epidemiological, clinical, economic and health-related quality of life evidence in activated PI3Kδ syndrome (APDS).系统性文献综述，以识别活化磷脂酰肌醇-3-激酶δ综合征（APDS）的流行病学、临床、经济和健康相关生活质量证据。
BMC Immunol. 2025 Jul 19;26(1):52. doi: 10.1186/s12865-025-00723-6.
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Overall survival among patients with activated phosphoinositide 3-kinase delta syndrome (APDS).活化磷脂酰肌醇3-激酶δ综合征（APDS）患者的总生存期。
Orphanet J Rare Dis. 2025 May 3;20(1):212. doi: 10.1186/s13023-025-03734-z.
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Genetic Etiologies and Outcomes in Malignancy and Mortality in Activated Phosphoinositide 3-Kinase Delta Syndrome: A Systematic Review.
活化磷脂酰肌醇3-激酶δ综合征的遗传病因与恶性肿瘤及死亡率的结局：一项系统综述
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