基于冥想的干预措施治疗强迫症：一项符合 PRISMA 原则的系统评价和荟萃分析。

Meditation-based intervention for obsessive-compulsive disorder: A PRISMA-compliant systematic review and meta-analysis.

机构信息

Department of Clinical Korean Medicine, Graduate School, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemoon-gu, Seoul, Republic of Korea.

College of Korean Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemoon-gu, Seoul, Republic of Korea.

出版信息

Medicine (Baltimore). 2022 Jul 29;101(30):e29147. doi: 10.1097/MD.0000000000029147.

DOI:10.1097/MD.0000000000029147

PMID:35905202

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9333541/

Abstract

BACKGROUND

The purpose of this study was to investigate the effects of the meditation-based intervention on obsessive-compulsive disorder (OCD).

METHODS

The following databases were searched up to April 2021: the Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, Medline (via PubMed), PsycARTICLES, 4 Korean databases (Korean Medical Database [KMbase], Koreanstudies Information Service System [KISS], National Digital Science Library [NDSL], and Oriental Medicine Advanced Searching Integrated System [OASIS]), and China National Knowledge Infrastructure (CNKI). The search terms related to meditation-based intervention and OCD were used. This systematic review was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. The selected articles were evaluated using the Cochrane risk of bias tool. The Review Manager (RevMan) 5.4 was used to perform the meta-analysis.

RESULTS

In all, 16 randomized controlled trials were selected. The meta-analysis showed that the group receiving the treatment combining medication and meditation-based intervention for OCD showed a more significant post-treatment improvement in Yale-Brown obsessive compulsive scale than the group receiving medication only. Compared with other non-medication interventions that are known to be effective in treating OCD, the Yale-Brown obsessive compulsive scale showed a significant improvement immediately after the meditation-based intervention. However, no significant difference was found in the follow-up monitoring data across all examined cases.

CONCLUSION

This study was conducted to verify the effects of meditation-based intervention on OCD. The results suggested that combined treatment with medication and meditation-based intervention was more effective in treating OCD than medication alone; the positive effects of meditation-based intervention may be greater than the effects of other non-medication interventions. However, the lack of significant difference in the follow-up indicates that long-term effect of meditation-based interventions is unclear.

TRIAL REGISTRATION NUMBER

PROSPERO CRD42021244408.

摘要

背景

本研究旨在探讨基于冥想的干预对强迫症（OCD）的影响。

方法

截至 2021 年 4 月，检索了以下数据库： Cochrane 对照试验中心注册库（CENTRAL）、EMBASE、Medline（通过 PubMed）、PsycARTICLES、4 个韩国数据库（KMbase、KISS、NDSL 和 OASIS）以及中国知网（CNKI）。使用了与基于冥想的干预和 OCD 相关的检索词。本系统评价基于系统评价和荟萃分析的首选报告项目。使用 Cochrane 偏倚风险工具评估所选文章。RevMan 5.4 用于进行荟萃分析。

结果

共纳入 16 项随机对照试验。荟萃分析结果显示，接受药物治疗联合基于冥想的干预治疗 OCD 的组在耶鲁-布朗强迫量表上的治疗后改善程度显著优于仅接受药物治疗的组。与其他已知对 OCD 有效的非药物干预措施相比，基于冥想的干预措施在干预后即刻表现出明显改善。然而，在所有检查病例中，随访监测数据均未发现显著差异。