Wierda A, Verhoeff J, Dorresteijn J, Wensing T, van Dijk S
Vet Rec. 1987 Mar 28;120(13):297-9. doi: 10.1136/vr.120.13.297.
The effects of two glucocorticoid compounds (Dexamedium; Intervet. Voreen; Boehringer Ingelheim) were tested in 20 healthy and 28 ketotic dairy cows. Both compounds induced an increased blood glucose concentration and a temporary decrease in the milk yield of healthy dairy cows. Dexamedium reduced the milk yield only of cows producing 25 or more kg milk daily. Of 28 ketotic cows 22 were treated with one of the two glucocorticoid compounds, while the remaining six were treated orally with propylene glycol. After treatment all but one of the cows improved clinically within one week. Biochemical analysis of blood samples revealed that after treatment with any of the three therapeutic compounds some animals responded inadequately to therapy or relapsed after initial recovery.
在20头健康奶牛和28头患酮血症的奶牛身上测试了两种糖皮质激素化合物（地塞米松；英特威公司的Voreen；勃林格殷格翰公司）的效果。两种化合物均使健康奶牛的血糖浓度升高，产奶量暂时下降。地塞米松仅使日产奶量25公斤或更多的奶牛产奶量降低。28头患酮血症的奶牛中，22头用两种糖皮质激素化合物之一进行治疗，其余6头口服丙二醇。治疗后，除1头奶牛外，所有奶牛在一周内临床症状均有改善。对血样的生化分析表明，用三种治疗化合物中的任何一种治疗后，一些动物对治疗反应不佳或在最初恢复后复发。
