• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

股前外侧游离皮瓣重建下咽缺损:单中心回顾性分析。

Reconstruction of hypopharyngeal defects with anterolateral thigh free flap: A single-center retrospective analysis.

机构信息

Plastic and Reconstructive Surgery Division, San Giovanni-Addolorata Hospital, Rome, Italy.

Department of Plastic Reconstructive and Aesthetic Surgery, Sapienza Università of Rome, Rome, Italy.

出版信息

Am J Otolaryngol. 2022 Sep-Oct;43(5):103542. doi: 10.1016/j.amjoto.2022.103542. Epub 2022 Jul 25.

DOI:10.1016/j.amjoto.2022.103542
PMID:35905665
Abstract

INTRODUCTION

Reconstruction of expanded hypopharyngeal defects following laryngo-hypopharyngectomy for surgical treatment of primary is still a challenge for head and neck surgeons. Tradiotionally, jejunal or radial forearm flaps are the common reconstructive choice. Recently, the anterolateral thigh (ALT) free flap has served for pharyngoesophageal reconstruction. The goal of this work is to describe a retrospective analysis about a five-year single-center experience in the reconstruction of post-operative hypopharyngeal defects with ALT free flap.

METHODS

A single-center retrospective study was performed, including patients treated for patients who underwent tumor surgery involving hypopharynx with ALT free flap reconstruction from 2015 to 2020. Exclusion criteria were paediatric (0-18 years) patients, and the absence of follow-up.

RESULTS

The study included 23 adult patients. The mean size of the flap was 90 cm (range 60-130 cm). The mean time required to harvest the antero-lateral tight flap was 70 min (range 35-120 min). The median age was 46.3 years (SD 15.81, range: 19-84 years), with a gender female prevalence (F = 48, M = 33). Mean follow-up was 77.7 months (min 4-max 361, SD 72.46). One patient (4.4 %) showed a hypopharyngeal stenosis.

CONCLUSION

ALT free flap represents a successful and versatile reconstructive option for hypopharyngeal defects extended to oropharynx and/or larynx following total laryngectomy with circumferential or partial hypopharyngectomy, regardless of the functional and aesthetic results, with minimal donor-site complication.

摘要

介绍

喉咽切除术治疗原发性肿瘤后,扩大的咽下部缺损的重建仍然是头颈部外科医生面临的挑战。传统上,空肠或游离前臂皮瓣是常见的重建选择。最近,股前外侧(ALT)游离皮瓣已用于咽食管重建。本研究旨在描述五年单中心应用 ALT 游离皮瓣重建术后咽下部缺损的回顾性分析。

方法

对 2015 年至 2020 年期间接受肿瘤手术且涉及咽下部的患者,采用 ALT 游离皮瓣重建的患者进行了单中心回顾性研究。排除标准为儿科(0-18 岁)患者和无随访患者。

结果

本研究纳入了 23 例成年患者。皮瓣的平均大小为 90cm(范围 60-130cm)。获取前外侧皮瓣的平均时间为 70min(范围 35-120min)。中位年龄为 46.3 岁(标准差 15.81,范围:19-84 岁),女性患病率较高(F=48,M=33)。平均随访时间为 77.7 个月(最小 4 个月,最大 361 个月,标准差 72.46)。1 例患者(4.4%)出现咽下部狭窄。

结论

ALT 游离皮瓣是全喉切除术伴环状或部分咽下部切除术,或累及咽下部和/或喉的患者的一种成功且多用途的重建选择,无论功能和美容效果如何,供区并发症最小。

相似文献

1
Reconstruction of hypopharyngeal defects with anterolateral thigh free flap: A single-center retrospective analysis.股前外侧游离皮瓣重建下咽缺损:单中心回顾性分析。
Am J Otolaryngol. 2022 Sep-Oct;43(5):103542. doi: 10.1016/j.amjoto.2022.103542. Epub 2022 Jul 25.
2
Efficacy of free anterolateral thigh flap and free jejunum in reconstruction for hypopharyngeal and cervical esophagus.游离股前外侧皮瓣与游离空肠在下咽及颈段食管重建中的疗效比较。
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2022 Jul 28;47(7):888-894. doi: 10.11817/j.issn.1672-7347.2022.210763.
3
Functional Outcome Analysis After Anterolateral Thigh Flap Reconstruction of Pharyngoesophageal Defect.股前外侧皮瓣修复咽食管缺损后的功能结果分析
Ann Plast Surg. 2015 Aug;75(2):174-9. doi: 10.1097/SAP.0000000000000073.
4
Head and neck soft tissue reconstruction with anterolateral thigh flaps with various components: Development of an algorithm for flap selection in different clinical scenarios.股前外侧皮瓣的头颈部软组织重建:不同临床情况下皮瓣选择的算法发展。
Microsurgery. 2019 Oct;39(7):590-597. doi: 10.1002/micr.30495. Epub 2019 Jul 31.
5
Reconstruction of laryngopharyngectomy defects: Comparison between the supraclavicular artery island flap, the radial forearm flap, and the anterolateral thigh flap.喉咽切除术缺损的重建:锁骨下动脉岛状皮瓣、游离桡侧前臂皮瓣和股前外侧皮瓣的比较。
Microsurgery. 2019 May;39(4):310-315. doi: 10.1002/micr.30406. Epub 2018 Dec 17.
6
Suprastomal cutaneous monitoring paddle for free flap reconstruction of laryngopharyngectomy defects.用于喉咽切除术缺损游离皮瓣重建的颏下皮肤监测桨
JAMA Facial Plast Surg. 2013 Jul-Aug;15(4):287-91. doi: 10.1001/jamafacial.2013.845.
7
The use of chimeric-superthin anterolateral thigh flap in reconstruction of laryngopharyngoesophagectomy defects of hypopharyngeal cancer.应用嵌合型超薄股前外侧皮瓣修复下咽癌喉咽全切除术后缺损
Microsurgery. 2023 Sep;43(6):563-569. doi: 10.1002/micr.31021. Epub 2023 Feb 8.
8
Reconstructive options after total laryngectomy with subtotal or circumferential hypopharyngectomy and cervical esophagectomy.全喉切除联合次全或环周下咽切除及颈段食管切除术后的重建选择。
Curr Opin Otolaryngol Head Neck Surg. 2012 Apr;20(2):77-88. doi: 10.1097/MOO.0b013e328350a5cc.
9
Adipofascial anterolateral thigh free flap in hypopharyngeal and oropharyngeal reconstruction.股前外侧脂肪筋膜游离皮瓣在下咽和口咽重建中的应用。
Microsurgery. 2022 Sep;42(6):586-592. doi: 10.1002/micr.30863. Epub 2022 Jan 19.
10
Reconstruction of the hypopharynx with the anterolateral thigh flap: defect classification, method, tips, and outcomes.股前外侧皮瓣重建下咽:缺损分类、方法、技巧和结果。
Plast Reconstr Surg. 2011 Jan;127(1):161-172. doi: 10.1097/PRS.0b013e3181f95997.