Department of Internal Medicine, Ensemble Hospitalier de la Côte, Morges, Switzerland
Department of Anaesthesiology, CHUV and University of Lausanne, Lausanne, Switzerland.
BMJ Open. 2022 Jul 29;12(7):e057288. doi: 10.1136/bmjopen-2021-057288.
To assess the bidirectional association between chronic pain and both subjectively and objectively measured physical activity (PA).
Cross-sectional study.
Population-based sample in Lausanne, Switzerland, May 2014 to April 2017.
Non-stratified, representative sample of the population of Lausanne (Switzerland) aged 35-75 years. Participants were excluded if they had missing data for the pain or the PA questionnaires, for accelerometry (defined as >20% of non-wear time or duration <7 days) or for covariates.
Primary outcomes were association between chronic pain and previous, subjectively assessed PA (questionnaire), and subsequent, objectively assessed PA (accelerometry). Daily pain, pain duration, number of painful sites and pain intensity were assessed by questionnaire. PA was assessed by questionnaire 2 weeks prior and by accelerometry 2 weeks after completion of the pain questionnaire. PA was further categorised as sedentary (SED), light and moderate-to-vigorous PA.
2598 participants (52.9% women, mean age 60.5 years) had subjectively assessed PA. Multivariable analysis showed time spent in SED to be negatively associated with the number of painful sites: adjusted mean±SE 528±5, 522±7 and 502±7 min/day for 0, 1-2 and 3+ painful sites, respectively, p for trend <0.005. No other association was found between chronic pain and subjectively assessed PA categories. 2205 participants (52.8% women, mean age 61.7 years) had accelerometry-derived PA. No significant association between chronic pain and subsequent objectively assessed PA was found after multivariable analyses.
In this Swiss population-based cohort, no consistent association was found between chronic pain and PA. Hence, in the general population, chronic pain does not significantly impact time spent in PA.
评估慢性疼痛与主观和客观测量的体力活动（PA）之间的双向关联。
横断面研究。
瑞士洛桑的基于人群的样本，2014 年 5 月至 2017 年 4 月。
非分层的、具有代表性的洛桑（瑞士）人群样本，年龄在 35-75 岁之间。如果参与者在疼痛或 PA 问卷、加速度计（定义为>20%的非佩戴时间或持续时间<7 天）或协变量方面存在缺失数据，则将其排除在外。
主要结局是慢性疼痛与以前的、主观评估的 PA（问卷）以及随后的、客观评估的 PA（加速度计）之间的关联。通过问卷评估每日疼痛、疼痛持续时间、疼痛部位数量和疼痛强度。PA 通过问卷在完成疼痛问卷前两周和通过加速度计在完成疼痛问卷后两周进行评估。PA 进一步分为久坐（SED）、轻度和中高强度 PA。
2598 名参与者（52.9%为女性，平均年龄 60.5 岁）进行了主观的 PA 评估。多变量分析显示，SED 时间与疼痛部位数量呈负相关：调整后的平均±SE 分别为 528±5、522±7 和 502±7 分钟/天，用于 0、1-2 和 3+个疼痛部位，趋势 p<0.005。慢性疼痛与主观评估的 PA 类别之间没有发现其他关联。2205 名参与者（52.8%为女性，平均年龄 61.7 岁）进行了加速度计衍生的 PA 评估。多变量分析后，未发现慢性疼痛与随后的客观评估的 PA 之间存在显著关联。
在这项瑞士基于人群的队列研究中，慢性疼痛与 PA 之间没有一致的关联。因此，在一般人群中，慢性疼痛不会显著影响 PA 时间。
